| Sequence 1: | NP_005893.1 | Gene: | SMAD3 / 4088 | HGNCID: | 6769 | Length: | 425 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524610.1 | Gene: | Med / 43725 | FlyBaseID: | FBgn0011655 | Length: | 771 | Species: | Drosophila melanogaster |
| Alignment Length: | 709 | Identity: | 192/709 - (27%) |
|---|---|---|---|
| Similarity: | 261/709 - (36%) | Gaps: | 319/709 - (44%) |
- Green bases have known domain annotations that are detailed below.
|
Human 23 QNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSHRKGLPH 85
Human 86 VIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVL----------PPVLV 140
Human 141 --------------------------PRHTEIPAEF----PPLDDYSHSIPENTNFPAG-----I 170
Human 171 EPQSNIPET------PPPGYLSEDGETSDHQMN------------------HSMDA--GSPNLSP 209
Human 210 NPMSPA----------------------------------------------------------- 215
Human 216 ----------------------------------------------HNNLDLQP----------- 223
Human 224 ----------------------------------------------VTYCE-------------- 228
Human 229 ----------------------------------PAFWCSISYYELNQRVGETFH--ASQPSMTV 257
Human 258 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCN 321
Human 322 QRYGWHPA-TVCKIPPGCNLKIF--------------NNQEFAALLAQSV----NQGFE------ 361
Human 362 ------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SMAD3 | NP_005893.1 | MH1_SMAD_2_3 | 8..132 | CDD:199815 | 65/110 (59%) |
| Linker | 137..231 | 32/364 (9%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 165..208 | 16/73 (22%) | |||
| MH2_SMAD_2_3 | 224..414 | CDD:199826 | 95/271 (35%) | ||
| Sufficient for interaction with XPO4. /evidence=ECO:0000269|PubMed:16449645 | 271..324 | 26/53 (49%) | |||
| Med | NP_524610.1 | MH1_SMAD_4 | 42..166 | CDD:199816 | 65/110 (59%) |
| MH2_SMAD_4 | 543..760 | CDD:199823 | 92/216 (43%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3701 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||