DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rn and ZFP2

DIOPT Version :9

Sequence 1:NP_001262343.1 Gene:rn / 40879 FlyBaseID:FBgn0267337 Length:952 Species:Drosophila melanogaster
Sequence 2:NP_085116.2 Gene:ZFP2 / 80108 HGNCID:26138 Length:461 Species:Homo sapiens


Alignment Length:226 Identity:90/226 - (39%)
Similarity:119/226 - (52%) Gaps:19/226 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   442 NQAVAAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGS---------GRK-YQCKMCPQI 496
            ||.....|.::.|:..|.|:.   |......:|.|.|.....|         |.| |:|..|.:.
Human   105 NQCSKTFSQSSSLLKHQRIHT---GEKPYKCNVCGKHFIERSSLTVHQRIHTGEKPYKCNECGKA 166

  Fly   497 FSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQ 561
            ||...:|.:|.:.|..| |||:|.:|.|||..:|.|.||.|||.|.|||:|..|.:.|||..:|.
Human   167 FSQSMNLTVHQRTHTGE-KPYQCKECGKAFHKNSSLIQHERIHTGEKPYKCNECGKAFTQSMNLT 230

  Fly   562 QHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHK 626
            .|.|||||:|||:|..  |.|||||..:|..|.|.|..:||::|:.|.|.||...:|..|...|.
Human   231 VHQRTHTGEKPYECNE--CGKAFSQSMHLIVHQRSHTGEKPYECSQCGKAFSKSSTLTLHQRNHT 293

  Fly   627 ESKHLKTHICQYCGKSYTQETYLTKHMQKHA 657
            ..|..|   |..||||::|.|||.:|.:.|:
Human   294 GEKPYK---CNKCGKSFSQSTYLIEHQRLHS 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rnNP_001262343.1 C2H2 Zn finger 490..510 CDD:275368 6/19 (32%)
C2H2 Zn finger 519..539 CDD:275368 10/19 (53%)
zf-H2C2_2 531..556 CDD:290200 13/24 (54%)
zf-C2H2 545..567 CDD:278523 9/21 (43%)
C2H2 Zn finger 547..567 CDD:275368 8/19 (42%)
zf-C2H2_8 550..630 CDD:292531 35/79 (44%)
zf-H2C2_2 559..586 CDD:290200 15/26 (58%)
C2H2 Zn finger 575..597 CDD:275368 10/21 (48%)
C2H2 Zn finger 605..625 CDD:275368 7/19 (37%)
C2H2 Zn finger 636..656 CDD:275368 10/19 (53%)
ZFP2NP_085116.2 COG5048 99..451 CDD:227381 90/226 (40%)
C2H2 Zn finger 104..124 CDD:275368 5/18 (28%)
C2H2 Zn finger 132..152 CDD:275368 4/19 (21%)
C2H2 Zn finger 160..180 CDD:275368 6/19 (32%)
C2H2 Zn finger 188..208 CDD:275368 10/19 (53%)
C2H2 Zn finger 216..236 CDD:275368 8/19 (42%)
C2H2 Zn finger 244..264 CDD:275368 10/21 (48%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 10/19 (53%)
C2H2 Zn finger 328..348 CDD:275368
C2H2 Zn finger 356..376 CDD:275368
C2H2 Zn finger 384..404 CDD:275368
C2H2 Zn finger 412..432 CDD:275368
C2H2 Zn finger 440..460 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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