DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and znf362

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001072350.1	Gene:	znf362 / 779803	XenbaseID:	XB-GENE-5793620	Length:	403	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	122/290 - (42%)
Similarity:	164/290 - (56%)	Gaps:	53/290 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   403 GLGLGASNGV----GGGGGGASVVGNSSLGASSHHAVAAAHHHNQAVAAA--------------- 448
            ||||.:|..:    ..|.|.:|:..::...:|....:|.:......:.:|
Frog   104 GLGLSSSRSIVSTSESGTGTSSITPSTPTSSSQTRLIATSPTLISGITSAPTLDSLKTIQGHSLL 168

  Fly   449 -----------------SAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQI 496
                             ....:||||.||.||     |.:          |..|:.|:||:||..
Frog   169 GPTKPERGRKKIKAENPPGPPVLVVPYPILAS-----GDI----------GKEGKTYRCKVCPLT 218

  Fly   497 FSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQ 561
            |.:|:::|:|::.| .||||:||..|||:|||:|||:||.|||||:|||.|..|::.|.||||||
Frog   219 FFTKSEMQIHSKSH-TEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQ 282

  Fly   562 QHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHK 626
            ||.|.||||:||||..|||:|||:||||||||.|.|..|||:||.:||:.::|..||..|:..|
Frog   283 QHTRIHTGDRPYKCPQPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAH- 346

  Fly   627 ESKHLKTHICQYCGKSYTQETYLTKHMQKH 656
            ..||.|.:.|..||::||.||||.|||.||
Frog   347 AIKHAKAYCCSMCGRAYTSETYLMKHMSKH 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	8/19 (42%)
		C2H2 Zn finger	519..539	CDD:275368	13/19 (68%)
		zf-H2C2_2	531..556	CDD:290200	15/24 (63%)
		zf-C2H2	545..567	CDD:278523	13/21 (62%)
		C2H2 Zn finger	547..567	CDD:275368	12/19 (63%)
		zf-C2H2_8	550..630	CDD:292531	47/79 (59%)
		zf-H2C2_2	559..586	CDD:290200	20/26 (77%)
		C2H2 Zn finger	575..597	CDD:275368	16/21 (76%)
		C2H2 Zn finger	605..625	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	12/19 (63%)
znf362	NP_001072350.1	C2H2 Zn finger	212..232	CDD:275368	8/19 (42%)
		zf-H2C2_2	224..249	CDD:404364	13/25 (52%)
		zf-C2H2	238..260	CDD:395048	14/21 (67%)
		C2H2 Zn finger	240..260	CDD:275368	13/19 (68%)
		zf-H2C2_2	252..277	CDD:404364	15/24 (63%)
		C2H2 Zn finger	268..288	CDD:275368	12/19 (63%)
		SFP1	<290..342	CDD:227516	32/51 (63%)
		C2H2 Zn finger	296..318	CDD:275368	16/21 (76%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	358..376	CDD:275368	11/17 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12078
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto103211
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000