DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and znf384

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	XP_012821830.1	Gene:	znf384 / 448352	XenbaseID:	XB-GENE-979648	Length:	564	Species:	Xenopus tropicalis

Alignment Length:	187	Identity:	103/187 - (55%)
Similarity:	126/187 - (67%)	Gaps:	6/187 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 SGRK-YQCKMCPQIFSSKADLQ----LHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIK 543
            ||.| |.|..|.:.|...:.||    :||::|...:|||||..|||.|||||||.||.|||.|.|
Frog   324 SGVKPYNCSYCQKAFRQLSHLQQHSRIHTKVHSIVSKPYKCPHCSKTFANSSYLHQHLRIHSGAK 388

  Fly   544 PYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSC 608
            ||.|..||:.|.||||||||.|.||||:||||.||||.|||:||||||||.|.|..||||||::|
Frog   389 PYNCNYCQKAFRQLSHLQQHTRIHTGDRPYKCVHPGCDKAFTQLSNLQSHRRQHNKDKPFKCHNC 453

  Fly   609 YKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPP 665
            ::.::|..:|..|:..| ..||.|.:.|..|.::||.||||.|||:||.....::||
Frog   454 HRAYTDASALEVHLSTH-TVKHAKVYTCSICSRAYTSETYLMKHMRKHNAPEPQQPP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	7/23 (30%)
		C2H2 Zn finger	519..539	CDD:275368	14/19 (74%)
		zf-H2C2_2	531..556	CDD:290200	15/24 (63%)
		zf-C2H2	545..567	CDD:278523	14/21 (67%)
		C2H2 Zn finger	547..567	CDD:275368	13/19 (68%)
		zf-C2H2_8	550..630	CDD:292531	48/79 (61%)
		zf-H2C2_2	559..586	CDD:290200	21/26 (81%)
		C2H2 Zn finger	575..597	CDD:275368	17/21 (81%)
		C2H2 Zn finger	605..625	CDD:275368	5/19 (26%)
		C2H2 Zn finger	636..656	CDD:275368	11/19 (58%)
znf384	XP_012821830.1	C2H2 Zn finger	214..234	CDD:275368
		COG5048	<241..453	CDD:227381	80/128 (63%)
		C2H2 Zn finger	242..262	CDD:275368
		C2H2 Zn finger	270..290	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	331..351	CDD:275368	5/19 (26%)
		C2H2 Zn finger	364..384	CDD:275368	14/19 (74%)
		C2H2 Zn finger	392..412	CDD:275368	13/19 (68%)
		C2H2 Zn finger	420..442	CDD:275368	17/21 (81%)
		C2H2 Zn finger	450..470	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	11/19 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12078
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000