DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and trem

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_650861.1	Gene:	trem / 42392	FlyBaseID:	FBgn0038767	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	181	Identity:	59/181 - (32%)
Similarity:	88/181 - (48%)	Gaps:	16/181 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 SGRK---YQCKMCPQI--FSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIK 543
            ||||   |. |..|::  |..|...:...::     ..|.|..|...:...:.|::|.:.|.|:|
  Fly   240 SGRKPVAYH-KNSPKVETFKKKVGRKPRNKL-----STYICDVCGNIYPTQARLTEHMKFHSGVK 298

  Fly   544 PYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSC 608
            |:.||||.|.|.|...|.:|:.||||::||||.:  |..||:..|....|.|.|..::|:.|:.|
  Fly   299 PHECEICGRGFVQNQQLVRHMNTHTGNRPYKCNY--CPAAFADRSTKTKHHRIHTKERPYVCDVC 361

  Fly   609 YKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAER 659
            .:.|:...:|..|...|...   |.|:|..|||.:.:...|..|.:.|..|
  Fly   362 SRTFTYSDNLKFHKMIHTGE---KPHVCDLCGKGFVKAYKLRLHRETHNRR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	4/21 (19%)
		C2H2 Zn finger	519..539	CDD:275368	4/19 (21%)
		zf-H2C2_2	531..556	CDD:290200	12/24 (50%)
		zf-C2H2	545..567	CDD:278523	9/21 (43%)
		C2H2 Zn finger	547..567	CDD:275368	9/19 (47%)
		zf-C2H2_8	550..630	CDD:292531	28/79 (35%)
		zf-H2C2_2	559..586	CDD:290200	13/26 (50%)
		C2H2 Zn finger	575..597	CDD:275368	7/21 (33%)
		C2H2 Zn finger	605..625	CDD:275368	5/19 (26%)
		C2H2 Zn finger	636..656	CDD:275368	6/19 (32%)
trem	NP_650861.1	zf-AD	11..87	CDD:214871
		COG5048	<264..411	CDD:227381	50/156 (32%)
		C2H2 Zn finger	274..294	CDD:275368	4/19 (21%)
		zf-H2C2_2	287..311	CDD:290200	12/23 (52%)
		C2H2 Zn finger	302..322	CDD:275368	9/19 (47%)
		zf-H2C2_2	315..338	CDD:290200	12/24 (50%)
		C2H2 Zn finger	330..350	CDD:275368	7/21 (33%)
		zf-H2C2_2	345..367	CDD:290200	7/21 (33%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		zf-H2C2_2	370..394	CDD:290200	9/26 (35%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100