Protein Alignment rn and gl

DIOPT Version :10

• Sequence 1: NP_001262343.1
• Gene: rn / 40879
• FlyBaseID: FBgn0267337
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001262708.1
• Gene: gl / 42210
• FlyBaseID: FBgn0004618
• Length: 679
• Species: Drosophila melanogaster
• Alignment Length: 663
• Identity: 153/663 - (23%)
• Similarity: 226/663 - (34%)
• Gaps: 191/663 - (28%)

  Fly   224 FGSSIKSPPSEPDAVTAATCKSQENNSGQNPTP-NSLSD--------HNPAHNL-----NSNSTA 274
            ||.::.||..|    .||:|....:..|....| :||:.        .:|...:     ..:...
  Fly    51 FGLALDSPQQE----CAASCVGCLSCQGSTALPISSLTSSDFDCGGCFDPTIGVGVGIGGGHIQI 111

  Fly   275 AAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHMTG--QTHHDP-------GAVGMHY 330
            :....|::...::|...||  |.:...|  :|.:..||....|  ....||       ...|..|
  Fly   112 STTPPASSGNGSSNNGAGG--GSSGNHG--YWSTDEMASTFPGLPPLDIDPLPSLFPFSPCGASY 172

  Fly   331 MW-NGNVDHAKDISDYNLWPP----TPRSHQHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDD 390
            .: .||...|..:| |.:.|.    :|.||.|...|   |..|:::     |..:.:|..|
  Fly   173 NFAAGNPHQAASLS-YTVHPHQMLISPNSHNHGQMH---SQHQQHQ-----HQQSQVQASH---- 224

  Fly   391 NRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASS-----------------------H 432
              :.:..:...||..:|::...||....||....:|.|.::                       |
  Fly   225 --VGNSLLQSSGGNNIGSNGSAGGVANAASCYYETSAGTAAPPPPPAAAMYPSMSVNVSMNMTMH 287

  Fly   433 HAVAAAH---------------HHNQAVAAASAAALLVV-------------------------- 456
            |...|..               ..|...|||:|||:.|:
  Fly   288 HGYGAGDAGGVPMQCSQMNWTPPSNSTSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAPA 352

  Fly   457 --------PQPINASKMGGPGGVSSVAGGHATGGG---------SGRKYQCKMCPQIFS------ 498
                    |..:...:...|...||:||.:.||.|         |...||........|
  Fly   353 PTGLGALPPLTVGEKESPSPPANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDEE 417

  Fly   499 -SKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQ 562
             |..||.........|.||..|..|.|.:|..|.|..|.|.|.|.:||||..|.:.|:|.::|..
  Fly   418 DSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTA 482

  Fly   563 HIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKE 627
            |:|||||.||::|  |.|.:.|||.|::.:|.|.|..::|::|:||.|.|||..:|.:|:..|..
  Fly   483 HVRTHTGQKPFRC--PICDRRFSQSSSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSG 545

  Fly   628 SKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPANGP 692
            .   |.:.|:.|...::|...|.:||:.|.......           .:..|...||.::..:|
  Fly   546 E---KPYQCKLCLLRFSQSGNLNRHMRVHGNNNSSN-----------GSNGATGVGGESSTGSG- 595

  Fly   693 PPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQQQQQQQ 757
                                 ....|.... ..|.||...              |..........
  Fly   596 ---------------------VGGGNSLLTXQKPRSAGGF--------------QHYHPPHTHHM 625

  Fly   758 QQQQQAHHHHPQH 770
            ..|..|||||..|
  Fly   626 HHQHHAHHHHHAH 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	4/26 (15%)
		C2H2 Zn finger	519..539	CDD:275368	8/19 (42%)
		COG5048	543..>647	CDD:227381	41/103 (40%)
		C2H2 Zn finger	547..567	CDD:275368	7/19 (37%)
		zf-H2C2_2	559..586	CDD:463886	13/26 (50%)
		C2H2 Zn finger	575..597	CDD:275368	9/21 (43%)
		C2H2 Zn finger	605..625	CDD:275368	9/19 (47%)
		C2H2 Zn finger	636..656	CDD:275368	6/19 (32%)
gl	NP_001262708.1	COG5048	<426..571	CDD:227381	57/149 (38%)
		C2H2 Zn finger	439..459	CDD:275368	8/19 (42%)
		C2H2 Zn finger	467..487	CDD:275368	7/19 (37%)
		C2H2 Zn finger	495..515	CDD:275368	9/21 (43%)
		C2H2 Zn finger	523..543	CDD:275368	9/19 (47%)
		C2H2 Zn finger	551..571	CDD:275368	6/19 (32%)