DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and CG42726

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	87/375 - (23%)
Similarity:	144/375 - (38%)	Gaps:	69/375 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 YQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQR 552
            |.|.:|.:.|.|:.....|........|.:.|.:|.:.||.||:|..|...|.....:.|.:|.:
  Fly    72 YHCTVCNKDFRSRTQQYYHLTCGNDLLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHK 136

  Fly   553 KFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCH-QTDKPFKCNSCYKCFSDEP 616
            .|.|...||:|:.||..:| :.|  |.|||.|.:.|:|.||...| .....|||..|.|.|.::.
  Fly   137 SFKQPIVLQRHMLTHNQEK-HLC--PICQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKA 198

  Fly   617 SLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAA 681
            :|.:|:.||  .|:...|:|:.|.||:.::|.|..||::|:.|..:               :.:.
  Fly   199 NLNQHLRKH--DKNNIRHMCKVCQKSFLRQTTLRLHMKRHSNRERQ---------------SCSL 246

  Fly   682 AGGSANPANGPPPPPNPAQHQRNNLGLP-------PVSIAPSDN--GYWPKVSPDSAAAANAMEV 737
            .|.|.|      .|....:|.|.:....       .::|...||  .:...:.|..|.|:....|
  Fly   247 CGKSYN------DPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRHLRSMHPGCAFASTVEMV 305

  Fly   738 MHQQQQQQQQQQQQQQQQ--------------------------------QQQQQQQAHHHHPQH 770
            ..:...|:....:::..|                                |.::.:....|.|..
  Fly   306 TPRSSAQEATTAEERPSQTVRYNSVIQSVGNVEPVMLLQSTPLPSQLPELQMEKGKAVPEHLPLP 370

  Fly   771 GVPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQPTAPNGSQS 820
            .|.|:::|...::.......:.:..:..|..|.....|: ||..|....|
  Fly   371 DVMPEENVQLYRKIILDLDNEEYSSEPSPDAQEPAMQHH-QPRVPGQGSS 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	5/19 (26%)
		C2H2 Zn finger	519..539	CDD:275368	8/19 (42%)
		zf-H2C2_2	531..556	CDD:290200	6/24 (25%)
		zf-C2H2	545..567	CDD:278523	7/21 (33%)
		C2H2 Zn finger	547..567	CDD:275368	7/19 (37%)
		zf-C2H2_8	550..630	CDD:292531	30/80 (38%)
		zf-H2C2_2	559..586	CDD:290200	12/26 (46%)
		C2H2 Zn finger	575..597	CDD:275368	10/21 (48%)
		C2H2 Zn finger	605..625	CDD:275368	6/19 (32%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	5/19 (26%)
		C2H2 Zn finger	103..123	CDD:275368	8/19 (42%)
		COG5048	<112..288	CDD:227381	57/201 (28%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	38/128 (30%)
		C2H2 Zn finger	158..178	CDD:275368	10/21 (48%)
		C2H2 Zn finger	187..207	CDD:275368	6/19 (32%)
		C2H2 Zn finger	216..236	CDD:275368	8/19 (42%)
		C2H2 Zn finger	244..264	CDD:275368	6/25 (24%)
		C2H2 Zn finger	272..290	CDD:275368	3/17 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100