DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rn and Zfp362

DIOPT Version :9

Sequence 1:NP_001262343.1 Gene:rn / 40879 FlyBaseID:FBgn0267337 Length:952 Species:Drosophila melanogaster
Sequence 2:NP_001074567.1 Gene:Zfp362 / 230761 MGIID:2652839 Length:418 Species:Mus musculus


Alignment Length:382 Identity:144/382 - (37%)
Similarity:183/382 - (47%) Gaps:99/382 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   347 LWPPTPRSH----------QHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDDNRLEHHAVTGQ 401
            |.||.|...          |.....||.|:.|                    .|..|.....|..
Mouse    70 LVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQ--------------------PDVALHARPATST 114

  Fly   402 -GGLGLGA-------SNGVGGGGGGAS------VVGNSSLGASSHHAVAA--------------- 437
             .||||.:       |....|.|.|.|      ....|.|.|||...::.               
Mouse   115 VTGLGLSSRTPAVSTSESTPGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQG 179

  Fly   438 --------AHHHNQAVAAASAAA--LLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKM 492
                    :....:.:.|.:...  :||||.||.||            |..|.   .|:.|:||:
Mouse   180 HGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILAS------------GETAK---EGKTYRCKV 229

  Fly   493 CPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQL 557
            ||..|.:|:::|:|::.| .||||:||..|||:|||:|||:||.|||||:|||.|..|.:.|.||
Mouse   230 CPLTFFTKSEMQIHSKSH-TEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQL 293

  Fly   558 SHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHI 622
            ||||||.|.||||:||||.||||:|||:||||||||.|.|..|||:||.:||:.:||..||..|:
Mouse   294 SHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHL 358

  Fly   623 PKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHA-----------ERTDKRPPIVP 668
            ..| ..||.|.:.|..||::||.||||.|||.||.           :||:.  |.:|
Mouse   359 SAH-AIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTES--PGIP 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rnNP_001262343.1 C2H2 Zn finger 490..510 CDD:275368 8/19 (42%)
C2H2 Zn finger 519..539 CDD:275368 13/19 (68%)
zf-H2C2_2 531..556 CDD:290200 15/24 (63%)
zf-C2H2 545..567 CDD:278523 13/21 (62%)
C2H2 Zn finger 547..567 CDD:275368 12/19 (63%)
zf-C2H2_8 550..630 CDD:292531 49/79 (62%)
zf-H2C2_2 559..586 CDD:290200 21/26 (81%)
C2H2 Zn finger 575..597 CDD:275368 17/21 (81%)
C2H2 Zn finger 605..625 CDD:275368 8/19 (42%)
C2H2 Zn finger 636..656 CDD:275368 12/19 (63%)
Zfp362NP_001074567.1 PRK14971 <27..>131 CDD:237874 16/80 (20%)
C2H2 Zn finger 227..247 CDD:275368 8/19 (42%)
zf-H2C2_2 239..264 CDD:404364 13/25 (52%)
zf-C2H2 253..275 CDD:395048 14/21 (67%)
C2H2 Zn finger 255..275 CDD:275368 13/19 (68%)
zf-H2C2_2 267..292 CDD:404364 15/24 (63%)
C2H2 Zn finger 283..303 CDD:275368 12/19 (63%)
SFP1 <305..357 CDD:227516 34/51 (67%)
C2H2 Zn finger 311..333 CDD:275368 17/21 (81%)
C2H2 Zn finger 341..361 CDD:275368 8/19 (42%)
C2H2 Zn finger 373..391 CDD:275368 11/17 (65%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BF42
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm43024
orthoMCL 1 0.900 - - OOG6_109421
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3082
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.740

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