Protein Alignment rn and lin-29

DIOPT Version :10

• Sequence 1: NP_001262343.1
• Gene: rn / 40879
• FlyBaseID: FBgn0267337
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001407503.1
• Gene: lin-29 / 174830
• WormBaseID: WBGene00003015
• Length: 460
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 195/521 - (37%)
• Similarity: 240/521 - (46%)
• Gaps: 130/521 - (24%)

  Fly   399 TGQGG---LGLGASNGVGGG-----------GGGASVVGNSSLGASSHHAVA------AAHHHNQ 443
            ||.|.   .|:|.:..|...           |..:..|..|:....:||::.      :.|..:.
 Worm    23 TGSGSTTHFGVGTNFSVRSSSRSTDGTDSTDGANSDNVTGSTGSTPAHHSITNLNMALSQHSIDS 87

  Fly   444 AVAAASA--------AALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSK 500
            |.||:|.        |.||...|             :|:...|...       |....|| |..|
 Worm    88 ATAASSTNPFPHFNQADLLNFHQ-------------NSLLPHHMFS-------QFGRYPQ-FEQK 131

  Fly   501 ADL-QLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPY-RCEICQRKFTQLSHLQQH 563
            .|: .|..|:.||||||||||||.||||||||||||.||||||||: .|..|.:|||||||||||
 Worm   132 PDVGVLQQQMQMREAKPYKCTQCVKAFANSSYLSQHMRIHLGIKPFGPCNYCGKKFTQLSHLQQH 196

  Fly   564 IRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKES 628
            ||||||:|||||:..||.|||||||||||||||||||||||||||||||:||.|||:||||||||
 Worm   197 IRTHTGEKPYKCKFTGCDKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFTDEQSLLDHIPKHKES 261

  Fly   629 KH---LKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPAN 690
            ||   ||.|||.:|||||||:|||.|||.|||:|                 :.|:..|....||:
 Worm   262 KHLKRLKIHICPFCGKSYTQQTYLQKHMTKHADR-----------------SKASNFGNDVVPAD 309

  Fly   691 GPPPPP----NPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQ 751
             |..|.    ||.|...:|         ..|:..:...|.....|||.|............|...
 Worm   310 -PFDPSLLSWNPMQGMGDN---------AHDSSSFNISSLTDQFAANTMIGSQSTNYNPAFQNSA 364

  Fly   752 QQQQQQQQQQQAHHHHP---QHG--VPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQ 811
            ..|....:..:....:|   ::|  .|....:.|.:..|:.
 Worm   365 FSQLFNIRNNRYLSEYPTSTKNGERAPGFNMITPLENIQRY------------------------ 405

  Fly   812 PTAPNGSQSNGHGAELQPHHRMPDPVREDIASTPSAVGPYDAASITKTTSNSAFTP---INSMPP 873
                |||.|:...........:       ::||||:.....|.|  .::....|.|   ||:|..
 Worm   406 ----NGSSSSATAVVTATGSAV-------VSSTPSSTSSSSAGS--SSSQGGVFNPQSLINNMKN 457

  Fly   874 H 874
            |
 Worm   458 H 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	7/20 (35%)
		C2H2 Zn finger	519..539	CDD:275368	17/19 (89%)
		COG5048	543..>647	CDD:227381	86/107 (80%)
		C2H2 Zn finger	547..567	CDD:275368	15/19 (79%)
		zf-H2C2_2	559..586	CDD:463886	21/26 (81%)
		C2H2 Zn finger	575..597	CDD:275368	17/21 (81%)
		C2H2 Zn finger	605..625	CDD:275368	16/19 (84%)
		C2H2 Zn finger	636..656	CDD:275368	14/19 (74%)
lin-29	NP_001407503.1	zf-C2H2	149..171	CDD:395048	19/21 (90%)
		C2H2 Zn finger	151..171	CDD:275368	17/19 (89%)
		zf-H2C2_2	163..189	CDD:463886	17/25 (68%)
		zf-C2H2_8	179..255	CDD:464935	62/75 (83%)
		C2H2 Zn finger	180..200	CDD:275368	15/19 (79%)
		zf-H2C2_2	192..219	CDD:463886	21/26 (81%)
		C2H2 Zn finger	208..230	CDD:275368	17/21 (81%)
		C2H2 Zn finger	238..258	CDD:275368	16/19 (84%)
		zf-C2H2	270..292	CDD:395048	16/21 (76%)
		C2H2 Zn finger	272..292	CDD:275371	14/19 (74%)