DRSC/TRiP Functional Genomics Resources

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Protein Alignment rn and ZNF362

DIOPT Version :9

Sequence 1:NP_001262343.1 Gene:rn / 40879 FlyBaseID:FBgn0267337 Length:952 Species:Drosophila melanogaster
Sequence 2:NP_001357141.1 Gene:ZNF362 / 149076 HGNCID:18079 Length:420 Species:Homo sapiens


Alignment Length:559 Identity:163/559 - (29%)
Similarity:223/559 - (39%) Gaps:208/559 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   158 KPHNNNGYSW-------STGNNNEVVSHSSN---GHTNNHPTTPPT----------PPNEASATQ 202
            :|..||.|.|       |..:|..:::....   ......|..|||          ||..|.::|
Human    16 EPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQ 80

  Fly   203 ATSVSAINLNQ-----------------AQPASQTRSNFGSSIKSPPSEPDAVTAATCKSQENNS 250
            |. :|...|.|                 |:||:.|.:..|.|.::|          :..:.|:::
Human    81 AV-MSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLSTRTP----------SVSTSESSA 134

  Fly   251 GQNPTPNSLSDHNPAHNLNSNSTAAAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHM 315
            |......:.:...|    .:.|.:..:|::....:....|        |.               
Human   135 GAGTGTGTSTPSTP----TTTSQSRLIASSPTLISGITSP--------PL--------------- 172

  Fly   316 TGQTHHDPGAVGMHYMWNGNVDHAKDISDYNLWPPTPRSHQHASEHHPMSLKQEYEAKMNDHHHN 380
                                :|..|.|..:.|..| |:     ||.....:|.|           
Human   173 --------------------LDSIKTIQGHGLLGP-PK-----SERGRKKIKAE----------- 200

  Fly   381 NLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASSHHAVAAAHHHNQAV 445
                                              ..||..|                        
Human   201 ----------------------------------NPGGPPV------------------------ 207

  Fly   446 AAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIH 510
                    ||||.||.||            |..|.   .|:.|:||:||..|.:|:::|:|::.|
Human   208 --------LVVPYPILAS------------GETAK---EGKTYRCKVCPLTFFTKSEMQIHSKSH 249

  Fly   511 MREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKC 575
             .||||:||..|||:|||:|||:||.|||||:|||.|..|.:.|.||||||||.|.||||:||||
Human   250 -TEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKC 313

  Fly   576 RHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCG 640
            .||||:|||:||||||||.|.|..|||:||.:||:.:||..||..|:..| ..||.|.:.|..||
Human   314 PHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAH-AIKHAKAYCCSMCG 377

  Fly   641 KSYTQETYLTKHMQKHA-----------ERTDKRPPIVP 668
            ::||.||||.|||.||.           :||:.  |.:|
Human   378 RAYTSETYLMKHMSKHTVVEHLVSHHSPQRTES--PGIP 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rnNP_001262343.1 C2H2 Zn finger 490..510 CDD:275368 8/19 (42%)
C2H2 Zn finger 519..539 CDD:275368 13/19 (68%)
zf-H2C2_2 531..556 CDD:290200 15/24 (63%)
zf-C2H2 545..567 CDD:278523 13/21 (62%)
C2H2 Zn finger 547..567 CDD:275368 12/19 (63%)
zf-C2H2_8 550..630 CDD:292531 49/79 (62%)
zf-H2C2_2 559..586 CDD:290200 21/26 (81%)
C2H2 Zn finger 575..597 CDD:275368 17/21 (81%)
C2H2 Zn finger 605..625 CDD:275368 8/19 (42%)
C2H2 Zn finger 636..656 CDD:275368 12/19 (63%)
ZNF362NP_001357141.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..28 5/11 (45%)
PRK14971 <27..>125 CDD:237874 20/98 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 54..80 7/25 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 115..155 7/53 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 178..202 8/74 (11%)
C2H2 Zn finger 229..249 CDD:275368 8/19 (42%)
zf-H2C2_2 241..266 CDD:372612 13/25 (52%)
zf-C2H2 255..277 CDD:333835 14/21 (67%)
C2H2 Zn finger 257..277 CDD:275368 13/19 (68%)
zf-H2C2_2 269..294 CDD:372612 15/24 (63%)
C2H2 Zn finger 285..305 CDD:275368 12/19 (63%)
SFP1 <307..359 CDD:227516 34/51 (67%)
C2H2 Zn finger 313..335 CDD:275368 17/21 (81%)
C2H2 Zn finger 343..363 CDD:275368 8/19 (42%)
C2H2 Zn finger 375..393 CDD:275368 11/17 (65%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BF42
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm40954
orthoMCL 1 0.900 - - OOG6_109421
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3082
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.740

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