DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and si:ch211-229l10.11

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	XP_021331165.1	Gene:	si:ch211-229l10.11 / 103910550	ZFINID:	ZDB-GENE-110913-131	Length:	850	Species:	Danio rerio

Alignment Length:	405	Identity:	114/405 - (28%)
Similarity:	174/405 - (42%)	Gaps:	74/405 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 SLKQEYEAKMNDHHHN------------NLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGG 417
            |.||....|::...||            ::.:.|:||.|...|   ||:...
Zfish   102 SFKQNVTLKIHMRTHNEERIFTCTQCGKSISQKHYLDINMRIH---TGEKPY------------- 150

  Fly   418 GASVVGNS--SLGASSHHAVA-----------AAHHHNQAVAAASAAALLVVPQPINASKMGGPG 469
            ..:..|.|  ..|:..||.::           ...:.||:........:....:|...::.|...
Zfish   151 TCTECGKSFPYKGSLKHHRISHTGEKPFTCTQCGKNFNQSSHLNQHMRIHTGEKPFTCTQCGKSF 215

  Fly   470 GVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQ 534
            ..|:....|.......:.:.|..|.:.||:.|:|..|.:||..| ||:.||||.|:|:.||||:|
Zfish   216 SYSANLNQHMRIHTGEKPFTCTQCGKSFSNSANLNQHMRIHTGE-KPFTCTQCGKSFSQSSYLNQ 279

  Fly   535 HTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQT 599
            |.|||.|.||:.|..|.:.|:|..:|.||:|.|||:||:.|..  |.|:|||.|:|..|.|.|..
Zfish   280 HMRIHTGEKPFTCTQCGKSFSQSPYLNQHMRIHTGEKPFTCSQ--CGKSFSQSSSLYLHMRIHTG 342

  Fly   600 DKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRP 664
            :|||.|..|.|.||...:|..|:..|...   |...|..||||::|.|.|..||:.|   |.::|
Zfish   343 EKPFTCTQCGKSFSKSSNLNIHMRNHTGE---KPFTCLQCGKSFSQSTSLNLHMRIH---TGEKP 401

  Fly   665 PIVPGSAAAIAAAAAAAAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSA 729
                        ......|.|.:.::      ||..|.||::|..|.:....:..:      ..:
Zfish   402 ------------FTCTQCGKSFSQSS------NPNIHMRNHIGEKPFTCTQCEKSF------SQS 442

  Fly   730 AAANAMEVMHQQQQQ 744
            .:.|...::|..:::
Zfish   443 TSLNRQMMIHTGEKE 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	7/19 (37%)
		C2H2 Zn finger	519..539	CDD:275368	13/19 (68%)
		zf-H2C2_2	531..556	CDD:290200	13/24 (54%)
		zf-C2H2	545..567	CDD:278523	8/21 (38%)
		C2H2 Zn finger	547..567	CDD:275368	8/19 (42%)
		zf-C2H2_8	550..630	CDD:292531	34/79 (43%)
		zf-H2C2_2	559..586	CDD:290200	13/26 (50%)
		C2H2 Zn finger	575..597	CDD:275368	10/21 (48%)
		C2H2 Zn finger	605..625	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	10/19 (53%)
si:ch211-229l10.11	XP_021331165.1	C2H2 Zn finger	12..32	CDD:275368
		zf-H2C2_2	25..49	CDD:316026
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		zf-H2C2_2	80..105	CDD:316026	1/2 (50%)
		SFP1	<90..169	CDD:227516	17/82 (21%)
		C2H2 Zn finger	96..116	CDD:275368	4/13 (31%)
		C2H2 Zn finger	124..144	CDD:275368	4/19 (21%)
		C2H2 Zn finger	152..172	CDD:275368	5/19 (26%)
		COG5048	176..580	CDD:227381	96/315 (30%)
		C2H2 Zn finger	180..200	CDD:275368	2/19 (11%)
		C2H2 Zn finger	208..228	CDD:275368	3/19 (16%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		C2H2 Zn finger	264..284	CDD:275368	13/19 (68%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368	10/21 (48%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		C2H2 Zn finger	376..396	CDD:275368	10/19 (53%)
		COG5048	400..841	CDD:227381	12/82 (15%)
		C2H2 Zn finger	404..424	CDD:275368	6/25 (24%)
		C2H2 Zn finger	432..452	CDD:275368	1/25 (4%)
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	601..621	CDD:275368
		C2H2 Zn finger	629..649	CDD:275368
		C2H2 Zn finger	657..677	CDD:275368
		C2H2 Zn finger	685..705	CDD:275368
		C2H2 Zn finger	713..733	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
		C2H2 Zn finger	769..789	CDD:275368
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910