DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rn and znf367

DIOPT Version :9

Sequence 1:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	XP_002935020.3	Gene:	znf367 / 100492222	XenbaseID:	XB-GENE-986040	Length:	347	Species:	Xenopus tropicalis

Alignment Length:	381	Identity:	76/381 - (19%)
Similarity:	130/381 - (34%)	Gaps:	141/381 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   428 GASSHHAVAA----AHHHNQAVAAASAAALLVVPQPINASKMGGP-GGVSSVAGGHATGGGSGRK 487
            |.::|:...:    :.|...:|            :.::.::.||. ..::.|.|....|.|:||
Frog    74 GENAHNVTLSPGPISRHQTPSV------------ESVHTTRDGGARARIADVIGSSVAGVGAGR- 125

  Fly   488 YQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQR 552
                        :.|.....:..:|..:|.  .:..:...|.   .:|:...:     ||.||.|
Frog   126 ------------REDAAAGLRDGIRRGRPR--AETVRDLINE---GEHSSSRI-----RCNICNR 168

  Fly   553 KFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKC--NSCYKCFSDE 615
            .|.:...||.|.|||||::||.|.:|.|.|||:|...|::|.|.|..:|||.|  |.|...|
Frog   169 VFPREKSLQAHKRTHTGERPYLCDYPDCGKAFAQSGQLKTHQRLHTGEKPFVCSENGCLSRF--- 230

  Fly   616 PSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAA 680
                             ||..::|          :||.....:|.:
Frog   231 -----------------THANRHC----------SKHPYARLKREE------------------- 249

  Fly   681 AAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQ 745
                |:|         .|::          :.:|..|...|              ...|.:.|:|
Frog   250 ----SSN---------KPSK----------IQVADKDTAEW--------------LAKHWETQEQ 277

  Fly   746 Q---------QQQQQQQQQQQQQQQQAHHHHPQHGVPPQQHVPPQQQQQQQQQQQH 792
            .         |:..|:||...:..|.......::|    .|...::..|:|:::.|
Frog   278 LPPTLKVKSIQKADQEQQDPLEYFQSDEEEDDKNG----SHSASRRCLQEQRERMH 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368	1/19 (5%)
		C2H2 Zn finger	519..539	CDD:275368	2/19 (11%)
		zf-H2C2_2	531..556	CDD:290200	7/24 (29%)
		zf-C2H2	545..567	CDD:278523	10/21 (48%)
		C2H2 Zn finger	547..567	CDD:275368	9/19 (47%)
		zf-C2H2_8	550..630	CDD:292531	31/81 (38%)
		zf-H2C2_2	559..586	CDD:290200	16/26 (62%)
		C2H2 Zn finger	575..597	CDD:275368	10/21 (48%)
		C2H2 Zn finger	605..625	CDD:275368	4/21 (19%)
		C2H2 Zn finger	636..656	CDD:275368	3/19 (16%)
znf367	XP_002935020.3	COG5048	<157..263	CDD:227381	44/182 (24%)
		C2H2 Zn finger	163..183	CDD:275368	9/19 (47%)
		C2H2 Zn finger	191..213	CDD:275368	10/21 (48%)
		C2H2 Zn finger	221..240	CDD:275368	7/48 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910