Protein Alignment Syt4 and SYT12

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_024304534.1
• Gene: SYT12 / 91683
• HGNCID: 18381
• Length: 487
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 110/427 - (25%)
• Similarity: 196/427 - (45%)
• Gaps: 79/427 - (18%)

  Fly    68 SGQPPHYLKKSPSPTGGKQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQ-------QNGN 125
            ||..|     ||||........|.....:|.:...:..|        ||.:|::       ....
Human   111 SGSFP-----SPSPFPNYDYRYLQQKYGESCAEAREKRV--------PAWNAQRASTRGPPSRKG 162

  Fly   126 QLTVVD------GNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNGKELTVTDQYGK---LG 181
            .|::.|      ..|....:...|..:|..|:.......:|:..|       :|::.:|:   ||
Human   163 SLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSIS-------SVSNTFGQDFTLG 220

  Fly   182 TIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDP-YVKLQLLPDKQHK 245
            .:...:.|....:.|.|::::.:.|                ..|.:|:.:. ::::.||||:|..
Human   221 QVEVSMEYDTASHTLNVAVMQGKDL----------------LEREEASFESCFMRVSLLPDEQIV 269

  Fly   246 VKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDIS 310
            ..:|:.||..:..:||.|:. .|:...|:..||.|.:...|...|:...|.|...|:.:::
Human   270 GISRIQRNAYSIFFDEKFSI-PLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL---- 329

  Fly   311 KEALSISKEIQPRS--LKIRAQGR-----GELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLAD 368
                    .:||.|  |.::.|.:     ||:|:||.:.|.|.|||||::||:||...:....||
Human   330 --------PLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 386

  Fly   369 PYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTK 433
            |:||:|||.:|::::||||.||:...:|||||:..|.:||     ..|:.:||.:.:.:.....:
Human   387 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPA-----IVLQDLSLRVTVAESSSDGR 446

  Fly   434 NEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWH 470
            .:.:|.:.: ||::|.....|||::..:.||.::.||
Human   447 GDNVGHVII-GPSASGMGTTHWNQMLATLRRPVSMWH 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	29/146 (20%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	53/144 (37%)
SYT12	XP_024304534.1	C2	218..329	CDD:326325	29/127 (23%)
		C2B_Synaptotagmin-12	350..485	CDD:176051	53/139 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820