Protein Alignment Syt4 and TCB3

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_013639.1
• Gene: TCB3 / 854903
• SGDID: S000004537
• Length: 1545
• Species: Saccharomyces cerevisiae
• Alignment Length: 449
• Identity: 87/449 - (19%)
• Similarity: 148/449 - (32%)
• Gaps: 143/449 - (31%)

  Fly    92 PMQDQST-SPIAQPNV-------KYSEEGDG--------PAQHAEQQNGNQLTVVDGNG------ 134
            |:.|.|| .||..||.       .|.:.|..        |..:..:::......|..||
Yeast   844 PIFDNSTYVPIFSPNQILTLEFHDYQKIGKDRFIGSVQIPTSNVFKKDPKSGKYVGNNGKEEISK 908

  Fly   135 LKHSLHNSLHHSPVETIANGSVT-----ITLDDHSLTNGKEL--TVTDQYGKLGTIYFKLRYLAE 192
            ||...|   .|...|:|.|.|.|     :......|.|.::|  .:.::..|......:.....|
Yeast   909 LKLKDH---EHKVTESIVNVSTTFIPINLVYSPEELVNVEKLEKELKEKKKKFEATQEENEQEME 970

  Fly   193 RNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPY----------VKL---QLLPDKQH 244
            :|.....:....                          ||:          .||   :|:..|..
Yeast   971 KNPKEWEVAEIE--------------------------DPFDSDEKKINRKAKLSLNELIKQKSG 1009

  Fly   245 KVKTRVVRNTRNP------VYDEDFTF-----------------YGLNMNDLQNMSLHFVILSFD 286
            .:..:::..|.:|      :..:|.::                 ..:.:.||....|||
Yeast  1010 ILSMQILEGTLSPSSAYLEILADDISYPVFICMKPSQGKLNSEMANIFIRDLNYSKLHF------ 1068

  Fly   287 RYSR-------DDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIRAQGRGELLISLCWQPA 344
            |.|:       ||||.|.            |...|.:.|:.....:.:...| .::.:...:.|.
Yeast  1069 RVSKKHIAKDSDDVISET------------SYSTLKLLKQAYEEPMWLNFNG-SKMKVRFLYTPT 1120

  Fly   345 A------------GRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPV 397
            :            |.|.:.|:....|...|..|.:||:|.|::  |.:::.  |:::||:||.||
Yeast  1121 SVKLPSSESVEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFV--NDKKVF--KSNIKKKTLDPV 1181

  Fly   398 FNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWN 456
            :||.....|       .|.....:...:|||||...|:.:|:..|...:.......:||
Yeast  1182 WNEDAKIPI-------LSRSKNQVIFNVLDWDRAGDNDDLGQASLDVSSLEVGKTYNWN 1233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	27/185 (15%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	33/137 (24%)
TCB3	NP_013639.1	COG5038	44..1335	CDD:227371	87/449 (19%)