Protein Alignment Syt4 and sytl1

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001122005.1
• Gene: sytl1 / 777759
• ZFINID: ZDB-GENE-060503-439
• Length: 539
• Species: Danio rerio
• Alignment Length: 549
• Identity: 127/549 - (23%)
• Similarity: 201/549 - (36%)
• Gaps: 191/549 - (34%)

  Fly    40 RLRNKKQSQHDASFPFQPTRRPTAVRSPSGQPPHYLKKSPSPTGG----------KQMGLLSPM- 93
            |:|..:|:..|          |..:||.||...|..:......||          |:.|...|:
Zfish    37 RVRKLQQTVSD----------PVHLRSLSGAWFHEERSKRYEKGGADVVHASLRRKRRGKDLPLT 91

  Fly    94 -----------------QDQSTSPIAQPNV------KYSEEGDGPAQHAEQQNGNQLTV------ 129
                             :|::.....|.|:      |:.|:.:...:..|....|.:|:
Zfish    92 AIFDKGNNSSHVHEQQEEDRNAERDLQGNMNEREDDKHQEQKESGQEDGESLISNAITIPQSRTR 156

  Fly   130 -------VDGNGLKHSLHNSLHH--------SPVETIAN----------------GSVTITLDDH 163
                   :.|:|.:.|:..|.:.        ||...|.:                |||| :|..|
Zfish   157 NVTKRNEILGSGFEDSVEESENKERRILPSTSPTLQIDSEGDIDSGSTEINYTRFGSVT-SLTSH 220

  Fly   164 SLTNGKELTV--TDQYGKL---GTIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMN 223
            .:.||..:::  ...:|.:   |.|.|.|:|......|.|.||||:            |:.:...
Zfish   221 HMMNGSLMSLYSVGDFGDVVVSGRIQFSLQYDVRTEELYVHIIRCQ------------DLASARK 273

  Fly   224 GRTQAATDPYVKLQLLPD--KQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFD 286
            .|    :|||||:.||||  .:.|.||.|.|.|.||||||..| |.:...||....|...:...:
Zfish   274 NR----SDPYVKVYLLPDNTSRSKKKTAVRRKTLNPVYDETMT-YKVRRLDLPARVLSMSVWHME 333

  Fly   287 RYSRDDVIGEVVCPLTSIEIG--DISKEALSISKEIQP--RSLKIRAQ-------GRGELLISLC 340
            |..|:..:||:     .:.:|  |.|:.        ||  ::|:.|.|       .||.:|.|:.
Zfish   334 RMRRNLFLGEL-----EVRLGQWDWSQN--------QPTWQNLQPRVQLSPEAIISRGTILFSIK 385

  Fly   341 W---------QPAAGRLTVVLLKARN-LPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLS 395
            :         .||.|.|.:.|.:... ||..  .|..:.|||..:|.:...::.::|.|.:.::|
Zfish   386 FVPPGSEGRGNPATGELHIWLREIVGLLPTK--RGAPNTYVKSVVLPDESGVSGQQTRVVRGSVS 448

  Fly   396 PVFNESFAFD---------------------------IPAAEGAGASLEGVSLELMLLDWDRVTK 433
            ||||.:..:|                           :..:.|:|.|. |.|     :.|...|:
Zfish   449 PVFNHTMVYDGFQSSDLIQACAEITVWNPHPSGCLGGVRLSTGSGLSY-GQS-----VCWMDSTE 507

  Fly   434 NEVIGRLELGGPNSSSTALNHWNEVCNSP 462
            :|:                |.|:.|..||
Zfish   508 DEI----------------NVWSSVIQSP 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	46/149 (31%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	37/168 (22%)
sytl1	NP_001122005.1	PHD_SF	12..>43	CDD:304600	2/5 (40%)
		C2A_SLP-1_2	242..364	CDD:176039	48/151 (32%)
		C2B_SLP_1-2-3-4	377..531	CDD:175987	37/168 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810