Protein Alignment Syt4 and Tc2n

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001076445.1
• Gene: Tc2n / 74413
• MGIID: 1921663
• Length: 489
• Species: Mus musculus
• Alignment Length: 392
• Identity: 88/392 - (22%)
• Similarity: 158/392 - (40%)
• Gaps: 79/392 - (20%)

  Fly    88 GLLSPMQDQSTSPIAQPNVKYSEEGDG----PAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSPV 148
            ||...|.|.:||     :.::.:..|.    |:..:.::|        ..|...||.
Mouse   169 GLSKSMLDLTTS-----SQRFIQRHDSFSSVPSSSSSRKN--------SQGSNRSLD-------- 212

  Fly   149 ETIANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGSS 213
                    ||||      :|.|       ..||.:..||.|.:....:.:::::||.:   ...|
Mouse   213 --------TITL------SGDE-------RDLGRLNVKLFYNSSAEQIWITVLQCRDI---SWPS 253

  Fly   214 GTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSL 278
            ..||.||           ..:|..|...|....|:.....:....:.|.|.| .:.:.:||.:.|
Mouse   254 SYGDTPT-----------ISIKGILTLSKPVHFKSSAKEGSNAIEFMETFVF-AIKLQNLQAVRL 306

  Fly   279 HFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKE-IQPRSLKIRAQGRGELLISLCWQ 342
            .|.|.:  :..:...|||  |   |:.:..:|.:.:..|.| |.|..:.:   .:.||.:..|:|
Mouse   307 AFKIQT--QTPKKKTIGE--C---SLSLRTLSTQEMEYSLEIIAPSKISV---CQAELELGTCFQ 361

  Fly   343 PAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPV-FNESFAFDI 406
            ....|:.:.:|:|:.||..........:||:.:..:|:.|.||||.:.|.:...| :.|:..|.:
Mouse   362 AVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPL 426

  Fly   407 PAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHK 471
            ...|      :.:...:.|.....|.:...:|:|.:...:::..|:|.|.|...:|.:.:.:|||
Mouse   427 IQTE------KEIVFLIKLYSRSSVRRKHFVGQLWISEDSNNIEAVNQWKETITNPEKVVIKWHK 485

  Fly   472 LN 473
            ||
Mouse   486 LN 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	33/143 (23%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	34/141 (24%)
Tc2n	NP_001076445.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..214		6/48 (13%)
		C2A_Tac2-N	239..341	CDD:176066	26/123 (21%)
		C2B_Tac2-N	352..486	CDD:176074	33/139 (24%)
		Nuclear localization signal	446..448		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810