DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syt4 and Pla2g4d

DIOPT Version :9

Sequence 1:	NP_477464.1	Gene:	Syt4 / 40876	FlyBaseID:	FBgn0028400	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_001080051.2	Gene:	Pla2g4d / 691905	RGDID:	1593372	Length:	825	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	58/244 - (23%)
Similarity:	99/244 - (40%)	Gaps:	39/244 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 LMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYD 260
            |.|.|:..|.||       ..|:        .:..||||.|:|......|.||:.|.|:.|||::
  Rat    33 LTVKILEARSLP-------RADL--------LSKADPYVTLRLPTASGRKFKTQTVTNSSNPVWN 82

  Fly   261 EDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSL 325
            |.|:|  |..:.::|: |...:...|..::||:..::...::.|..|.:.::..|::.: .|..|
  Rat    83 ETFSF--LIQSQVKNI-LELTVYDEDLITKDDICFKISYDISEILPGQLVQKTFSLNPQ-GPEEL 143

  Fly   326 KIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDV-------TGLADPYVKIYLLYNGQRIA 383
            .:      |.|:.....|....:|..:|.||.|..:||       |.:|....|:.|     .:.
  Rat   144 DV------EFLVERTCDPPENLITNNVLVARELSHLDVSLDRAGSTTMAAGQDKLEL-----ELM 197

  Fly   384 KKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVT 432
            .|.::...:|..|  :.:|.............|.|........||:..|
  Rat   198 LKGSYEDTQTFLP--DTAFTLSFHYMRSQDTELNGYLRSSRNSDWNSDT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	33/125 (26%)
Syt4	NP_477464.1	C2B_Synaptotagmin-4	332..473	CDD:176049	23/108 (21%)
Pla2g4d	XP_001080051.2	C2_cPLA2	32..151	CDD:176001	37/142 (26%)
		PLAc	267..758	CDD:214474
		Patatin_and_cPLA2	278..814	CDD:299702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900