Protein Alignment Syt4 and Syt4

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_113881.1
• Gene: Syt4 / 64440
• RGDID: 68397
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 181/478 - (37%)
• Similarity: 254/478 - (53%)
• Gaps: 90/478 - (18%)

  Fly    16 VPAILGLTAA----AVLSSVACICARQMRLRNKKQSQHDASFPFQPTRRPTAVRSPSGQPP---- 72
            :|.::|:.:|    ..:|..|.||.::...::.|                        .||
  Rat    14 IPTVVGIFSAFGLVFTVSLFAWICCQRRSAKSNK------------------------TPPYKFV 54

  Fly    73 HYLK---------KSPSPTGGKQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQ----NG 124
            |.||         .|....||..       :.::....|.||:         :.|.:.:    ||
  Rat    55 HVLKGVDIYPENLSSKKKFGGDD-------KSEAKRKAALPNL---------SLHLDLEKRDLNG 103

  Fly   125 NQLTVVDGNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRY 189
            |........|....|.|.......||...     .:...||.:...||..::..||||::..|.|
  Rat   104 NFPKTNPKAGSSSDLENVTPKLFPETEKE-----AVSPESLKSSTSLTSEEKQEKLGTLFLSLEY 163

  Fly   190 LAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNT 254
            ..|:.|.:|:|...:|||.....|.|              :|||:|:.:||:|:|||||||:|.|
  Rat   164 NFEKKAFVVNIKEAQGLPAMDEQSMT--------------SDPYIKMTILPEKKHKVKTRVLRKT 214

  Fly   255 RNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKE 319
            .:||:||.|||||:....:|.:||||.:|||||:|||||||||:.||:.||:.|   ..:.:::|
  Rat   215 LDPVFDETFTFYGVPYPHIQELSLHFTVLSFDRFSRDDVIGEVLVPLSGIELSD---GKMLMTRE 276

  Fly   320 IQPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAK 384
            |..|:.| ::.||||||:|||:|.....||||:||||:||:.||:||:|||||:.|.:..:||:|
  Rat   277 IIKRNAK-KSSGRGELLVSLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISK 340

  Fly   385 KKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSS 449
            |||||||.|.:.||||.|.||||.     .|||.:|:|.::||.:|.::|||||||.||.....|
  Rat   341 KKTHVKKCTPNAVFNELFVFDIPC-----ESLEEISVEFLVLDSERGSRNEVIGRLVLGATAEGS 400

  Fly   450 TALNHWNEVCNSPRRQIAEWHKL 472
            .. .||.|:|:.||||||:||.|
  Rat   401 GG-GHWKEICDFPRRQIAKWHML 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	66/142 (46%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	80/141 (57%)
Syt4	NP_113881.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..121		3/22 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..147		3/20 (15%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	48/125 (38%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	72/134 (54%)