Protein Alignment Syt4 and Syt8

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_445777.2
• Gene: Syt8 / 60566
• RGDID: 68399
• Length: 387
• Species: Rattus norvegicus
• Alignment Length: 285
• Identity: 89/285 - (31%)
• Similarity: 148/285 - (51%)
• Gaps: 37/285 - (12%)

  Fly   207 PCKGGSS-------------GTGDIPTGM----NGRTQAATDPYVKLQLLPDKQHKVKTRVVRNT 254
            ||.||..             |:.:|..|:    |.:.:...|||.::.:......:.:|:|.|.|
  Rat    98 PCSGGDQPWGQLLLSLEYDFGSQEIRVGLRQAKNLKAEGTADPYARVSVSTQAGRRHETKVHRGT 162

  Fly   255 RNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKE 319
            ..|:::|...|. :...:|...:|...:|.|.|:|..:.:||:..||.::::..:.:....:.
  Rat   163 LCPMFEETCCFL-VPPAELPKATLKVQLLDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLG-- 224

  Fly   320 IQPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAK 384
             .|.|.:  ::..|||..||.:.|::||||||:|:||.|.    .|||:.|||:.|:.|.::..|
  Rat   225 -PPGSTE--SEQMGELCFSLRYVPSSGRLTVVILEARGLN----PGLAEAYVKVQLILNQRKWKK 282

  Fly   385 KKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTK--NEVIGRLELGGPNS 447
            .||..||.|.:|.|||:|.|.:|.::     |:  |::|:|..|.|..:  .|.:|::.| ||.:
  Rat   283 NKTSSKKGTTNPYFNEAFVFLVPVSQ-----LQ--SMDLVLAVWARGLQLLAEPVGKVLL-GPRA 339

  Fly   448 SSTALNHWNEVCNSPRRQIAEWHKL 472
            |...|.||.::....||.||:||.|
  Rat   340 SGQPLQHWADMLAHARRPIAQWHHL 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	28/131 (21%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	59/143 (41%)
Syt8	NP_445777.2	Syt1_2_N	<27..72	CDD:425364
		C2	107..225	CDD:472691	24/121 (20%)
		C2	234..364	CDD:472691	58/141 (41%)