Protein Alignment Syt4 and sytl2b

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_701277.6
• Gene: sytl2b / 572466
• ZFINID: ZDB-GENE-121214-363
• Length: 1737
• Species: Danio rerio
• Alignment Length: 482
• Identity: 108/482 - (22%)
• Similarity: 191/482 - (39%)
• Gaps: 117/482 - (24%)

  Fly    28 LSSVACICARQMRLRNKKQSQHD----------ASFPFQPTRRPTAVRSPSGQPPHYLKKSPSPT 82
            :..::.|..:..:|:......||          .||   .|..|..::..|...|.:|:|...
Zfish  1315 MEDISSIARQDQKLKQTDDYMHDNYDASSTHLQTSF---STADPEHMKKLSKSVPSFLEKESD-- 1374

  Fly    83 GGKQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSP 147
            ||         :..|.|         |..|..|     :.|..|.|         :|.|....:.
Zfish  1375 GG---------ESDSES---------SSRGSVP-----KWNNRQFT---------NLSNYSGSTS 1407

  Fly   148 VETIANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGS 212
            :.:::....::...|::..:.:           |:|.|.|.|:.:.....:.:::|:.|......
Zfish  1408 LSSVSGSVASVYTSDYNSVDVQ-----------GSIQFSLNYVHKLREFHIFVVQCQNLAAVDAK 1461

  Fly   213 SGTGDIPTGMNGRTQAATDPYVKLQLLPDKQH--KVKTRVVRNTRNPVYDEDFTFYGLNMNDLQN 275
                          :..:|||||..|:||..:  |.||.|.:.|.||.|:| ...|.:.|..|.:
Zfish  1462 --------------RNRSDPYVKSYLIPDPANLGKRKTAVKKKTLNPTYNE-ILRYRVRMEYLTS 1511

  Fly   276 MSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSI---------SKEIQPRSLKIRAQG 331
            ..|:......|.:.|:..:||:...|::.:..|..::.|.:         :..:||..||    |
Zfish  1512 QVLNLSAWHNDMFGRNSFLGEIELDLSTWDFNDTERKLLPLKPRNLFIQTTNSLQPSDLK----G 1572

  Fly   332 RGELLISLCWQ-------PAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHV 389
            :..|.|....|       |.:|.:.:.:...:|||.:. :...|||||.::|.:..:.:::||.|
Zfish  1573 QMRLAIRFLPQISHSKNVPGSGEVHIWVKDCKNLPLIR-SPTIDPYVKCFVLPDTSKKSRQKTRV 1636

  Fly   390 KKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELG----------- 443
            .|||.:|:||.:..:|...||    .|:...:||.:.|.||:..:. :|.|.||
Zfish  1637 LKRTTNPIFNHTMVYDGFRAE----DLKEACVELTVWDRDRLASHS-LGGLRLGMGTGRSYGVQV 1696

  Fly   444 -GPNSSSTALNHWNEVCNSPRRQIAEW 469
             ..:|::..:..|..:.|||.    ||
Zfish  1697 DWMDSTTEEVALWRRMMNSPN----EW 1719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	35/153 (23%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	43/157 (27%)
sytl2b	XP_701277.6	PHD_SF	5..>47	CDD:304600
		C2	1429..1553	CDD:301316	35/149 (23%)
		C2B_SLP_1-2-3-4	1571..1727	CDD:175987	45/163 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810