Protein Alignment Syt4 and syt10

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_017210538.3
• Gene: syt10 / 564226
• ZFINID: ZDB-GENE-041210-297
• Length: 566
• Species: Danio rerio
• Alignment Length: 533
• Identity: 172/533 - (32%)
• Similarity: 262/533 - (49%)
• Gaps: 108/533 - (20%)

  Fly     3 EEYIPDASVMDTIVPAILGLTAAAVLSSVACICARQMRL-----RNKKQSQHDASFPFQPTRRP- 61
            |..|||.||  :::..::|....|:|.....:.   .:|     |:|..:.:..|.|      |
Zfish    58 ESNIPDISV--SLLAVVVGFCGLALLVVSLFVF---WKLCWPIWRSKAFTSNADSCP------PG 111

  Fly    62 TAVRSPSGQPPHYLKKSPSP-TGGKQMGLL--SPMQDQ-------------------STSPIAQP 104
            ..:.:|...||  :.:|.|| ...|.:|:.  .|.|.|                   |:..|.:.
Zfish   112 VLLEAPPAPPP--VSRSVSPYAEAKAVGVAGRQPSQIQHEDEEDKKWKVPEVKVNGRSSVKILEA 174

  Fly   105 NVKYSEEG-DGPAQHAE------------QQNGNQLTVVDGNGLKHSLHNSL-HHSPVETIANGS 155
            .:|.|:.. |.||:..:            |:...:.|       ..|.|||. .|.|.:.... |
Zfish   175 AMKISQTSPDIPAEVQQALRDRLSKQAKIQRQTTEPT-------SSSRHNSFRRHLPRQMNVT-S 231

  Fly   156 VTITLD------DHSLTNG-------KELTVTDQYG------KLGTIYFKLRYLAERNALMVSII 201
            |..|:|      ..:::.|       |:.:|..:.|      ..|.:.|.|.|..|..||:|.|:
Zfish   232 VDFTMDTLPVRQSSAVSIGRIKPELYKQKSVDSEEGTKEPVETCGKLSFALSYDYEEQALVVRIL 296

  Fly   202 RCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTFY 266
            :...||.| ..:||              :|||||:.|||:::.|.:|||.|.|.||.:||||.|
Zfish   297 KALDLPAK-DFTGT--------------SDPYVKIYLLPERKKKFQTRVHRKTLNPTFDEDFRF- 345

  Fly   267 GLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIRAQG 331
            .:..::|.|..|||.:..|||::..|:|||||.. ...|:.|:|:||: :.|:|...:.:  :..
Zfish   346 PVEYSELCNRKLHFSVYDFDRFTSHDMIGEVVVD-NLFELSDLSREAV-VWKDILAATTE--SVD 406

  Fly   332 RGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSP 396
            .||::.|||:.|.|||:|:.::|.|||..||:||.:|||||:.|:.:|:|:.|:||..||.||:|
Zfish   407 LGEIMYSLCYLPTAGRMTLTVIKCRNLKAMDITGYSDPYVKVALICDGRRLKKRKTTTKKNTLNP 471

  Fly   397 VFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNEVCNS 461
            |:||:..||||.     .::|.|||.:.::|:|||..|||||... .||::.....:||||:...
Zfish   472 VYNEAIIFDIPP-----ENVEQVSLSITVMDYDRVGHNEVIGVCR-AGPDAEGLGRDHWNEMLAY 530

  Fly   462 PRRQIAEWHKLNE 474
            ||:.|..||.|.|
Zfish   531 PRKPITHWHALCE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	56/142 (39%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	65/140 (46%)
syt10	XP_017210538.3	C2A_Synaptotagmin-1-5-6-9-10	274..399	CDD:176031	56/142 (39%)
		C2B_Synaptotagmin-3-5-6-9-10	408..541	CDD:176048	65/138 (47%)