Protein Alignment Syt4 and sytl2a

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_009303749.1
• Gene: sytl2a / 563188
• ZFINID: ZDB-GENE-130723-2
• Length: 1447
• Species: Danio rerio
• Alignment Length: 433
• Identity: 106/433 - (24%)
• Similarity: 180/433 - (41%)
• Gaps: 78/433 - (18%)

  Fly    63 AVRSPSGQPPHYLKKSPSPTGGKQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQL 127
            ::.:.|..||:.......|...|.|.|..|...|                    |..|.:|.:..
Zfish  1046 SMENVSAVPPNTKTSFSDPEQVKMMSLSVPALMQ--------------------QEMECRNSDCA 1090

  Fly   128 TVVDGNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNGKELTV-TDQYGKL---GTIYFKLR 188
            :|       .|.:|....| ..|.:|.|....:...|...|..::: :.::|.:   ||:.|.:.
Zfish  1091 SV-------SSFYNDRQRS-CNTPSNFSTCSEVASMSSVTGSVMSIYSSEFGYVEVKGTVQFAIH 1147

  Fly   189 YLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQH--KVKTRVV 251
            |:.:.....:.:::|:.|       ...|:       .:..:|||||..|||||..  |.||.|.
Zfish  1148 YVQKLGEFHIFVVQCKDL-------AVADV-------KRNRSDPYVKCYLLPDKAKYGKKKTCVR 1198

  Fly   252 RNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSI 316
            :.|.:|.|:|...| .:.|..|:...|:..:...|.:.|:..:|||...|...:..:.......:
Zfish  1199 KKTLDPTYNEILRF-KIPMEMLKTQKLNISVWHNDTFGRNSFLGEVEVDLAEWDFNNTQMNEYLL 1262

  Fly   317 SKEIQ-PRSLKIRAQGR---GELLISLCWQPAA---------GRLTVVLLKARNLPRMDVTGLA- 367
            ...:| |.|.|....|.   .|:.::|.:.|..         |.:.:.:.:.:|||..  .|:|
Zfish  1263 KGRVQIPTSPKHSFGGEEMSAEIKVALRFLPQTTLSHKNKGNGEVQIWVKECKNLPIS--RGVAI 1325

  Fly   368 DPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAG-ASLEGVSLELMLLDWDRV 431
            ||:||..:|....|.:::||.|.||..:||||.:..:|     |.| ..|:.:.:||.:.|.||:
Zfish  1326 DPFVKCAILPENNRKSRQKTRVLKRAPNPVFNHTMVYD-----GFGHDDLKDICVELTVWDHDRL 1385

  Fly   432 TKNEVIGRLELGGPNSSSTALNHWNEV--CNSPRRQIAEWHKL 472
             .|..||.:.||    ..|..::.:||  .:|...:.|.|.::
Zfish  1386 -NNHFIGGIRLG----PGTGKSYGSEVNWMDSNVAEAALWERM 1423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	36/148 (24%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	44/157 (28%)
sytl2a	XP_009303749.1	PHD_SF	5..>37	CDD:328929
		C2A_SLP-1_2	1139..1263	CDD:176039	35/138 (25%)
		C2B_SLP_1-2-3-4	1283..1438	CDD:175987	44/153 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810