Protein Alignment Syt4 and Syt6

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_006501767.1
• Gene: Syt6 / 54524
• MGIID: 1859544
• Length: 529
• Species: Mus musculus
• Alignment Length: 493
• Identity: 163/493 - (33%)
• Similarity: 241/493 - (48%)
• Gaps: 90/493 - (18%)

  Fly    23 TAAAVLSSVACICARQMRLRNKKQSQHDASFPF-------QPTRRPTAVRSPSGQPPHYLKKSPS 80
            |:.::|:.|..:|...:          .|.|.|       .|.|:..|....|..|.....:|||
Mouse    56 TSVSLLAVVVIVCGVAL----------VAVFLFLFWKLCWMPWRKKEASSPSSANPASETLQSPS 110

  Fly    81 PTGGKQMGLLSPMQDQSTSPIAQPNVKYSEEG-DGPAQ-----------HAEQQNGNQLTVVDGN 133
            ..|    .:...::|.|.....:..||.|... |.||:           |.:.|   :.|....:
Mouse   111 SRG----NMADKLKDPSALGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTKLQ---RQTTEPAS 168

  Fly   134 GLKHS-----LHNSLHHSPV------------ETIANGSVTITLDDHSLTNGKELTVTDQYGKLG 181
            ..:|:     |...:|.|.|            :..:.|.:...|......:|.: ..::.....|
Mouse   169 STRHTSFKRHLPRQMHVSSVDYGNELPPAAAEQPTSIGRIKPELYKQKSVDGDD-AKSEAAKSCG 232

  Fly   182 TIYFKLRYLAERNALMVSIIRCRGLPCKG--GSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQH 244
            .|.|.|||..|...|:|.|::...||.|.  |||                 |||||:.||||::.
Mouse   233 KINFSLRYDYESETLIVRILKAFDLPAKDFCGSS-----------------DPYVKIYLLPDRKC 280

  Fly   245 KVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDI 309
            |::|||.|.|.||.:||:|.| .:...:|.:..||..:..|||:||.|:||||:.. ...|..|:
Mouse   281 KLQTRVHRKTLNPTFDENFHF-PVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDL 343

  Fly   310 SKEALSISKEIQ---PRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYV 371
            |:|. ||.|:||   ..|:.:     ||::.|||:.|.|||||:.::|.|||..||:||.:||||
Mouse   344 SRET-SIWKDIQYATSESVDL-----GEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYV 402

  Fly   372 KIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEV 436
            |:.||.:|:|:.||||.:||.||:|::||:..||||.     .:::.|||.:.::|:|||..||:
Mouse   403 KVSLLCDGRRLKKKKTTIKKNTLNPIYNEAIIFDIPP-----ENMDQVSLLISVMDYDRVGHNEI 462

  Fly   437 IGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHKLNE 474
            ||...: |.|:.....:||||:...||:.||.||.|.|
Mouse   463 IGVCRV-GINAEGLGRDHWNEMLAYPRKPIAHWHSLVE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	59/147 (40%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	66/140 (47%)
Syt6	XP_006501767.1	C2A_Synaptotagmin-1-5-6-9-10	231..355	CDD:176031	58/143 (41%)
		C2B_Synaptotagmin-3-5-6-9-10	364..497	CDD:176048	66/138 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X61
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820