Protein Alignment Syt4 and syt1a

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001314758.1
• Gene: syt1a / 436736
• ZFINID: ZDB-GENE-040718-165
• Length: 419
• Species: Danio rerio
• Alignment Length: 434
• Identity: 137/434 - (31%)
• Similarity: 215/434 - (49%)
• Gaps: 101/434 - (23%)

  Fly    99 SPIAQPNV---KYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSP------------- 147
            :|.|.|.|   .....|.||.:..::....         :|:...|.||..|
Zfish    12 APTAAPEVPGNSTEAAGPGPRETKDEMFSK---------VKNKFMNELHKIPLPSWAIVAIAFVA 67

  Fly   148 ----------------------------------VETIANGSVTITLDDH-----SLTNGKELTV 173
                                              ::.:.:|..|..|.|.     .||:.::...
Zfish    68 VVLVVSCCFCICKKWIFKKKNKKKGKDKGKNAINMKDVKDGIKTEALKDEDDAETGLTDTEKEVE 132

  Fly   174 TDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPC--KGGSSGTGDIPTGMNGRTQAATDPYVKL 236
            ..:..|||.:.:.:.|....|.|:|.||:...||.  .||:|                 |||||:
Zfish   133 PKEEEKLGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTS-----------------DPYVKV 180

  Fly   237 QLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPL 301
            .|||||:.|.:|:|.|.|.|||::|.||| .:...:|...:|...:..|||:|:.|.||:|..|:
Zfish   181 YLLPDKKKKFETKVHRKTLNPVFNEQFTF-KVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPM 244

  Fly   302 TSIEIGDISKE---ALSISKEIQPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDV 363
            ..::...:::|   ..|..||.|.:        .|::..||.:.|.||:||||:|:|:||.:|||
Zfish   245 NKVDFSHVTEEWRDLQSAEKEEQEK--------LGDICFSLRYVPTAGKLTVVVLEAKNLKKMDV 301

  Fly   364 TGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDW 428
            .||:||||||:|:.||:|:.||||.:||.||:|.:||||:|::|..:     ::.|.:.:.:||:
Zfish   302 GGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQ-----IQKVQVVITVLDY 361

  Fly   429 DRVTKNEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHKL 472
            |::.||:.||::.: |.||:.|.|.||:::..:|||.||:||.|
Zfish   362 DKIGKNDAIGKVFV-GLNSTGTELRHWSDMLANPRRPIAQWHVL 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	51/147 (35%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	67/141 (48%)
syt1a	NP_001314758.1	Syt1_N	4..111	CDD:409248	13/107 (12%)
		C2A_Synaptotagmin-1-5-6-9-10	139..261	CDD:176031	47/139 (34%)
		C2B_Synaptotagmin-1	270..405	CDD:176047	67/141 (48%)