Protein Alignment Syt4 and Sytbeta

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 132/466 - (28%)
• Similarity: 198/466 - (42%)
• Gaps: 134/466 - (28%)

  Fly    50 DASFPFQPTRRPTAVRSPS-----GQPPHYLK----KSPSPT--------GGKQMG--------- 88
            :..||....|.|:.:|:.|     |.|.|...    ::|||:        ||..||
  Fly   223 EPGFPHHLARSPSPMRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGSSAGKGVA 287

  Fly    89 ---LLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSPVET 150
               .|||:   ...|.:||.|   :...|||...                 .:|...|:..|
  Fly   288 GGRCLSPL---LIPPRSQPGV---DPAMGPASPL-----------------GALQPDLYRMP--- 326

  Fly   151 IANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRYLAERNALMVSIIRCRGL-PCKGGSSG 214
              :|.|.:|..:.|             ..:|.::.:::|......|.|.:|....| |.:.|
  Fly   327 --DGPVYLTAPESS-------------HAVGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEG--- 373

  Fly   215 TGDIPTGMNGRTQAATDPYVKLQLLPD-KQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSL 278
                         ...||||:|.|.|: ...|.:|.:.|...||.:|:.|.| .::.:.||...|
  Fly   374 -------------GFRDPYVRLMLQPEVDSRKRQTHIHRGESNPYFDQHFKF-PVSRDQLQGKEL 424

  Fly   279 HFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIRA----QGRGELLISL 339
            ...:|.:||||.:|:||||          .||.:.|.:||.::.....:|.    :.|.|||.||
  Fly   425 ILQVLDYDRYSHNDIIGEV----------RISVDGLDLSKSVEIWGDLLRTKKPKEDRPELLCSL 479

  Fly   340 CWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKR--TLSPVFNESF 402
            .:.|.|.|||||::|||||..     |.:|||||||:.||:||.||||.:.|.  ..:|::||:|
  Fly   480 NYLPQAERLTVVIMKARNLDT-----LQEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAF 539

  Fly   403 AFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIG----RLELG----GPNSSSTALNHWNEVC 459
            .|::.:     ..|...::|:.           |:|    ..|:|    ||..|.|...||:::.
  Fly   540 TFNLQS-----NYLHNAAIEIY-----------VVGAGSEATEIGCCGLGPQESGTGCQHWHDMI 588

  Fly   460 NSPRRQIAEWH 470
            |:.|:..|.||
  Fly   589 NNARKPTAMWH 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	41/144 (28%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	57/149 (38%)
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	12/43 (28%)
		C2	341..463	CDD:472691	41/148 (28%)
		C2B_Synaptotagmin	473..601	CDD:175975	56/148 (38%)