Protein Alignment Syt4 and C2CD4B

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001007596.2
• Gene: C2CD4B / 388125
• HGNCID: 33628
• Length: 364
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 60/279 - (21%)
• Similarity: 97/279 - (34%)
• Gaps: 71/279 - (25%)

  Fly    46 QSQHDASFPFQPTRRPT-----AVRSPS---------GQPPHYLKKSPSPTGG----KQMG-LLS 91
            :||...|.|..|..|.|     .:.||.         |.||....::.|..||    ..:| |..
Human    81 RSQAALSLPHLPRVRTTYGFCALLESPHTRRKESLLLGGPPAPRPRAHSCGGGGGPDAPLGTLCG 145

  Fly    92 PMQDQSTSPIAQ--PNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLH--NSLHHSPVETIA 152
            |......:|.|.  |.:.......||      :....|.|.||. |..:|.  .|...:.|.:::
Human   146 PRGPGPATPAAPGGPRLPQDALAAGP------RRCRLLRVPDGL-LSRALRAGRSRRLARVRSVS 203

  Fly   153 NGSVTITLDDHSLTNGKE--------------LTVTDQYGKLGTIYF-----KLRYLAE----RN 194
            :|:     :|.....|.|              ..:.::....||:..     .||..||    ..
Human   204 SGN-----EDEERRAGSESPARAPSSSPLSSRAPLPERLEAKGTVALGRAGDALRLAAEYCPGTR 263

  Fly   195 ALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVY 259
            .|.:.::|...|  .||:.|    |..:..|......|       |.......:.||..:|...:
Human   264 RLRLRLLRAESL--FGGAPG----PRAVRCRLSLVLRP-------PGTARWQCSAVVGRSRKASF 315

  Fly   260 DEDFTFYGLNMNDLQNMSL 278
            |:||.|.||:.::::.:::
Human   316 DQDFCFDGLSEDEVRRLAV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	25/109 (23%)
		C2B_Synaptotagmin-4	332..473	CDD:176049
C2CD4B	NP_001007596.2	PHA03247	<10..300	CDD:223021	51/243 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..166		12/52 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..234		5/44 (11%)