Protein Alignment Syt4 and PLA2G4F

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_998765.3
• Gene: PLA2G4F / 255189
• HGNCID: 27396
• Length: 849
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 81/399 - (20%)
• Similarity: 132/399 - (33%)
• Gaps: 144/399 - (36%)

  Fly   141 NSLHHSPVETIANGSVTITLDDHSLTNGKELTVTDQYGKLGTIYFKLR----------------- 188
            |...|..:.......:.:||.|      |::..:||   |..:.|.||
Human    95 NETFHYQIHGAVKNVLELTLYD------KDILGSDQ---LSLLLFDLRSLKCGQPHKHTFPLNHQ 150

  Fly   189 --------YLAERNALMVSIIRCRGL----PC---KGGSSGTGDIPTGMNGRTQ---AATDPYVK 235
                    ::.|::.:..|.:...|:    ||   :|...|.|..|....|..|   |....|.|
Human   151 DSQELQVEFVLEKSQVPASEVITNGVLVAHPCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEK 215

  Fly   236 LQLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVIL----------SFDRYSR 290
            .||||          ::....|.....|||:   :|.:.:..||..::          |.:..::
Human   216 PQLLP----------LQPPTEPGLPPTFTFH---VNPVLSSRLHVELMELLAAVQSGPSAELEAQ 267

  Fly   291 DDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIRAQGRG-ELLISLCWQPAAGRLTVVLLK 354
            ...:||....|:|:.:|  .:|..|:            |.|.| |:.:|:..:.::|.|.:.|
Human   268 TSKLGEGGILLSSLPLG--QEEQCSV------------ALGEGQEVALSMKVEMSSGDLDLRL-- 316

  Fly   355 ARNLPRMDVTG--LADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFD-----IPAAEGA 412
                      |  |:|         ..|....::..|..:.|..|...|.|.|     :.|..|:
Human   317 ----------GFDLSD---------GEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVLGS 362

  Fly   413 G----------ASLEGVSLELMLLD-----------------------WDRVTKNEVIGRLELGG 444
            |          .||.|:. ||.|||                       |.:|.....|.|.::..
Human   363 GGGTRAMSSLYGSLAGLQ-ELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIERAQVHV 426

  Fly   445 PNSSSTALN 453
            .:|...||:
Human   427 CSSKMGALS 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	37/187 (20%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	34/163 (21%)
PLA2G4F	NP_998765.3	C2_cPLA2	46..163	CDD:176001	12/76 (16%)
		PLAc	295..791	CDD:214474	34/163 (21%)
		cPLA2_Grp-IVB-IVD-IVE-IVF	303..845	CDD:132840	31/155 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900