Protein Alignment Syt4 and tcb3

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_593974.1
• Gene: tcb3 / 2542267
• PomBaseID: SPAPYUK71.03C
• Length: 1225
• Species: Schizosaccharomyces pombe
• Alignment Length: 621
• Identity: 126/621 - (20%)
• Similarity: 203/621 - (32%)
• Gaps: 247/621 - (39%)

  Fly     6 IPDASVMDTIV--PAILGLTAAAVLSSVACICARQMRLRNKKQSQHDASFPFQPTRRPTA----- 63
            :||:....|.|  |.:|                 |..:...|:..:|      |::||||
pombe   557 VPDSGEEITKVDGPGVL-----------------QFTVHQCKELSND------PSKRPTAYAKLI 598

  Fly    64 VRSPSGQPPHYLKKSPSPTGGKQMGLLSP-----------MQDQSTSPIAQPNVK----YSEEGD 113
            :.:........:||:.:|:..:..|.|.|           ..::|..|....||.    ::....
pombe   599 INNKEVYTTRKIKKNNNPSWEESFGTLLPEGKNATLGVQIFTEESEHPFGTANVSLQDLFAATKT 663

  Fly   114 G----PAQHA-------------EQQNGNQLTVV--------------DGNGLKHSL-------- 139
            |    |.|||             .|.|.:.::.:              ..|.|...:
pombe   664 GLLWFPLQHAPSGRVRMSVMWKPAQLNNDSISSMALATPIGAIRIHLRSANNLHSKIPGKKCDSY 728

  Fly   140 -----HNSLH------------------HSPVET--------IAN----------GSVTITLDD- 162
                 ||:..                  ::||.|        :.|          |...|.:.:
pombe   729 ARIMSHNTKQFRTVVIASNVNPFWDEYMYAPVITKHDIFFLQVMNYNSSGEDKLIGQTPINISNF 793

  Fly   163 -HSLTNG--------KELTV--TDQYGKLG--TIYFKLRYLAERNALMVSIIRCRGLPCKGGSSG 214
             :...||        :||||  :...|..|  ||.||                |...|....:|.
pombe   794 INQGENGALMEYHDPRELTVPLSSTRGIKGNATITFK----------------CDFFPSAVTTSL 842

  Fly   215 TGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRV-----------VRNTR------------- 255
            :.|:.......:..|||. |.:::||:.| |..|.|           |:.::
pombe   843 SPDVTPAPKASSTVATDK-VNIEVLPESQ-KTPTAVDNTSTSRGSTSVKTSKPKKISELLMPSEA 905

  Fly   256 -NPVYDEDFTFYGLNM------NDLQNMSL------HFVILSFDRYSRDDVIGEVV--------- 298
             |...|.:..|.|.::      ...|.:::      |.:.||    |..:|.|...
pombe   906 VNAALDFESGFMGFDIISYKIAKPAQELAIFLDDLPHHIFLS----SALNVTGGATLHEYGNTFI 966

  Fly   299 -------CPLTSI----EIGDISKEALS---ISKEIQPRSLKIRAQGRGELLISLCWQPA----- 344
                   |....:    |:|  ||..||   |||. ..:.|:|.......:|::....|.
pombe   967 RQLEYSQCTFKLLDGDKEVG--SKTMLSRDLISKG-ATKPLEIAFPDGASILVAFRLTPVPVKLE 1028

  Fly   345 -------AGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESF 402
                   .|.:||.::||.:||..|..|.:||:|...|  .|:.:.:.|||  ||||:|.|||||
pombe  1029 EVEMYENMGEMTVDVIKATDLPAADSNGKSDPFVVFEL--QGEEVYRTKTH--KRTLNPTFNESF 1089

  Fly   403 AFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIG 438
            ..::|..:..       :....:.|||...|::.:|
pombe  1090 EVELPCKQTC-------NFVANVFDWDFGNKDDHLG 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	41/204 (20%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	35/119 (29%)
tcb3	NP_593974.1	COG5038	1..1225	CDD:227371	126/621 (20%)