Protein Alignment Syt4 and snt-5

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_503409.1
• Gene: snt-5 / 178631
• WormBaseID: WBGene00004925
• Length: 458
• Species: Caenorhabditis elegans
• Alignment Length: 501
• Identity: 138/501 - (27%)
• Similarity: 225/501 - (44%)
• Gaps: 109/501 - (21%)

  Fly    15 IVPAILGLTAAAVLSSVAC-----ICARQMRLRNKKQSQHDASFPFQPTRRPTAVRSPSGQPPHY 74
            ::.|||.| .|.:|||.|.     ||.||:: |..|.|:...|.|      ...|..|.......
 Worm     8 VLVAILSL-CAVILSSCALYFGARICVRQIK-RKVKYSEVPTSVP------EIKVSVPQSASTLS 64

  Fly    75 LKKSPSPTGGKQMGLLS------PMQDQS------TSPIAQPNVKYSEE-----GDGPAQHAEQQ 122
            :.|.   .|..:..:||      |..|::      :||...|.:..:.:     ||.|...:..:
 Worm    65 ISKM---NGSYRARVLSRNGCSPPWMDRNFETSTRSSPCTSPAIASTSDSCELLGDDPRSASSMR 126

  Fly   123 NGNQLTVVDGNGLKHSLHNSLHHSP-----VETIANGSVT-ITLDDHSLTNGKELTVTDQYGKLG 181
            |...|..||||             |     :|.|...||. ..|..:..|:|..:.        |
 Worm   127 NSMFLFNVDGN-------------PEVIDEMEDIDERSVMHYELGFYDKTDGGCIR--------G 170

  Fly   182 TIYFKLRYLAERNALMVSIIRCRGLPC--KGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQH 244
            |:.|.|||......||:.:||...||.  ||                 ...|||||:.|||:::.
 Worm   171 TLTFALRYDFIHRVLMLHVIRANNLPVEDKG-----------------VTVDPYVKMYLLPERRG 218

  Fly   245 KVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDI 309
            ..|||:.:.|.:|.::|.|:| .::.|:|.|..|.|.:..|||::|..:||.::. ....|..|:
 Worm   219 HCKTRICKKTNDPEFNEMFSF-DVSFNNLANRMLQFTVYDFDRFTRHGLIGNIIM-RDLFEKSDL 281

  Fly   310 ---SKEALSISKEIQPRSLKIRAQGR---GELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLAD 368
               ::..:.|          :.:|.:   |:||:.|.:.....:|.:.:.||.||..||:||.:|
 Worm   282 YTWTEYTMHI----------VASQNKNDYGDLLLFLTYSNQEEKLYINVSKAYNLRPMDITGASD 336

  Fly   369 PYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTK 433
            |||||...:||:|...||:..|:..|:|||:|:..||||:::     :...::.:.::||||:.|
 Worm   337 PYVKIEQTFNGKRFKSKKSSTKRANLNPVFHETLVFDIPSSQ-----IAETNILIQVMDWDRIGK 396

  Fly   434 NEVIGRLELGGPNSSSTALNHWNEVCNS-------PRRQIAEWHKL 472
            ::::|...||..:.::.....|:...|:       ..:.:.:||.|
 Worm   397 DDLLGCCILGKDSPTADGKTQWDNCLNAVPEEGQLKNKPVGQWHSL 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	44/147 (30%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	47/151 (31%)
snt-5	NP_503409.1	C2	169..277	CDD:472691	41/134 (31%)
		C2B_Synaptotagmin	301..442	CDD:175975	46/145 (32%)