Protein Alignment Syt4 and rbf-1

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001367825.1
• Gene: rbf-1 / 175943
• WormBaseID: WBGene00004316
• Length: 1123
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 134/570 - (23%)
• Similarity: 219/570 - (38%)
• Gaps: 146/570 - (25%)

  Fly     6 IPDA---SVMDTIV------PAILGLTAAAVLSSVACICARQMRLRNKKQSQHD----------A 51
            :|||   |:...:|      |...|||.::  ||:..:         ::|:.||          .
 Worm   593 LPDADTRSIDSGVVQSDHSNPQQSGLTCSS--SSLTPL---------QQQASHDHHSGGGTPRRI 646

  Fly    52 SFPFQPTRRPTAVRSPSG------QPPHYLKKSP---------------------SPTGGKQMGL 89
            |.|.:.|.|  ..:|.||      .||...:.||                     |..|.:::|.
 Worm   647 SNPDRTTSR--VAQSASGTSLVTPPPPISSRTSPDNCNSSPLNVMEHKSSSASTASSGGNRRVGS 709

  Fly    90 LSPMQD-------------------QSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGL 135
            ..|:.:                   ..||....|....|.....|....:|:|..:    ||.|.
 Worm   710 AEPVLNNHHAMHNNQNHNDINKKLISQTSRAESPLAASSSFLSSPDDDTKQKNRRR----DGVGR 770

  Fly   136 KHS--LHNSLHH--SPVETIA--NGSVTITLDDHSLTNG--------------------KELTVT 174
            .:|  |..||..  .||..|:  ||.:..:....|.|:.                    |.:|.:
 Worm   771 VNSLQLRTSLDDVAPPVAPISKMNGHIVSSEPTSSTTSNQNHTSVPIPTVPVVPEEEEEKAITAS 835

  Fly   175 ----DQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVK 235
                .:.|.||:|...|.|.:....|.:.:||.:.|.....           ||    .:|||||
 Worm   836 TESASEPGSLGSITLTLTYHSADKKLKMHLIRAKNLKAMDS-----------NG----FSDPYVK 885

  Fly   236 LQLLP--DKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVV 298
            ..|||  .|..|:.::.:..|.||.::|:.::||:..:|.:...|...:|..||.. .|.:||..
 Worm   886 FHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIG-SDFLGETR 949

  Fly   299 CPLTSIEIGDISKEALSISKEIQ-PRSLKIRA-QGRGELLISLCWQPAAGRLTVVLLKARNLPRM 361
            ..|..:...::.|..|.:...:. |:..|... :.||::.:.|.:....|.|.:.:.:...|..|
 Worm   950 IALKKLNDNEMKKFNLYLESALPVPQQTKEEENEDRGKINVGLQYNIQQGSLFININRCVELVGM 1014

  Fly   362 DVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLL 426
            |.||.:|||.|:.|.....:..:.||..|||||:|.:||...|.:|..:     |...:|::.:.
 Worm  1015 DSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKD-----LPKKTLQIGVY 1074

  Fly   427 DWDRVTKNEVIGRLELGGPNSSSTALN----HWNEVCNSPRRQIAEWHKL 472
            |.|....::.||.:.|     |::|.:    .|.:...:|...:..||:|
 Worm  1075 DHDLGKHDDYIGGILL-----STSAKDERGRQWIKCIENPGTLVEAWHRL 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	38/145 (26%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	41/145 (28%)
rbf-1	NP_001367825.1	FYVE_2	220..342	CDD:396754
		C2A_Rabphilin_Doc2	845..967	CDD:176000	38/137 (28%)
		C2B_Rabphilin_Doc2	987..1119	CDD:176030	38/141 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910