Protein Alignment Syt4 and Syt12

DIOPT Version :9

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_598925.1
• Gene: Syt12 / 171180
• MGIID: 2159601
• Length: 421
• Species: Mus musculus
• Alignment Length: 466
• Identity: 117/466 - (25%)
• Similarity: 208/466 - (44%)
• Gaps: 85/466 - (18%)

  Fly    20 LGLTAAAVLSSVACICARQMRLRNKKQSQHDASFPFQPTRRPTAVRSPSGQPPH---YL-KKSPS 80
            :|:.||..|:.:........:|..      ..|||           |||..|.:   || :|...
Mouse    21 VGVYAAGALALLGIAAVSLWKLWT------SGSFP-----------SPSPFPNYDYRYLQQKYGE 68

  Fly    81 PTGGKQMGLLSPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHH 145
            .....::..:.|..||.|:....|:.|.|...:...:...:....:|           :...|..
Mouse    69 AYVEAKLKRVPPWNDQRTTTRGPPSRKGSLSIEDTFESISELGPLEL-----------MGRELDL 122

  Fly   146 SPVETIANGSVTITLDDHSLTNGKELTVTDQYGK---LGTIYFKLRYLAERNALMVSIIRCRGLP 207
            :|..|:.......:|:..|       :|::.:|:   ||.:...:.|....:.|.|::::.:.|
Mouse   123 APYGTLRKSQSADSLNSIS-------SVSNTFGQDFTLGQVEVSMDYDGASHTLHVAVLQGKDL- 179

  Fly   208 CKGGSSGTGDIPTGMNGRTQAATDP-YVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMN 271
                           ..|.:|..:. ::::.||||:|....:|:.||..:..:||.|: ..|:..
Mouse   180 ---------------LEREEATFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFS-VPLDPT 228

  Fly   272 DLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEIQPRS--LKIRAQGR-- 332
            .|:..||.|.:...|...|:...|.|...|:.:::            .:||.|  |.::.|.:
Mouse   229 ALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL------------PLQPFSGWLYLQDQNKAA 281

  Fly   333 ---GELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTL 394
               ||:|:||.:.|.|.|||||::||:||...:....|||:||:|||.:|::::||||.||:...
Mouse   282 DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNEKSTADPFVKVYLLQDGRKMSKKKTAVKRDDP 346

  Fly   395 SPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNEVC 459
            :|||||:..|.:||     ..|:.:||.:.:.:.....:.:.:|.:.: ||..|.....|||::.
Mouse   347 NPVFNEAMIFSVPA-----IVLQDLSLRVTVAESSSDGRGDNVGHVII-GPGVSGMGTTHWNQML 405

  Fly   460 NSPRRQIAEWH 470
            .:.||.::.||
Mouse   406 ATLRRPVSMWH 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	29/146 (20%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	53/144 (37%)
Syt12	NP_598925.1	C2	152..263	CDD:301316	29/127 (23%)
		C2B_Synaptotagmin-12	284..419	CDD:176051	53/139 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820