Protein Alignment Syt4 and doc2a

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_031748920.1
• Gene: doc2a / 101730387
• XenbaseID: XB-GENE-922476
• Length: 391
• Species: Xenopus tropicalis
• Alignment Length: 408
• Identity: 121/408 - (29%)
• Similarity: 185/408 - (45%)
• Gaps: 88/408 - (21%)

  Fly    91 SPMQDQSTSPIAQPNVKYSEEGDGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSPVETIANGS 155
            ||..:::.||...|                                |:|      ||::....|:
 Frog    40 SPWPERTPSPTGNP--------------------------------HNL------SPLDIPPCGA 66

  Fly   156 VTITLDDHSLTNGKELTVTDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPT 220
            .  |.||.:..:..:   :|:...|||:.|.|.|..|:..|...|:|.:||.           |.
 Frog    67 E--TADDSADVDNYD---SDESTALGTLEFDLLYDPEQCILQCCILRAKGLK-----------PM 115

  Fly   221 GMNGRTQAATDPYVKLQLLPD--KQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVIL 283
            ..||    ..|||||:.|||.  |.:|:|||.|||:.||.::|..|:.|:...|:....|...:.
 Frog   116 DFNG----LADPYVKIHLLPGACKANKLKTRTVRNSLNPTWNESLTYCGITQEDMGKKILRISVC 176

  Fly   284 SFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEI---QPRSLKIRAQG-------------- 331
            ..|:.|.::.|||...||..::.|:.....|.:.::|   .|.|:....:|
 Frog   177 DEDKLSHNEFIGETRVPLRRLKPGERKHFNLCLERQIPLASPSSMTAALRGISCYLKELERCQEW 241

  Fly   332 ----RGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKR 392
                ||.:|:||.:....|.|.|.:::..:|..|||.|.:|||||.||..:.::.:|.||.|||:
 Frog   242 ELEERGRILLSLTYSSERGGLVVGIMRCAHLAAMDVNGFSDPYVKTYLKPDVEKKSKHKTVVKKK 306

  Fly   393 TLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNE 457
            ||:|.|||.|.::|...|     |:..|||:.:.|:|....|:.||.:.. |.:|....|.||.|
 Frog   307 TLNPEFNEEFFYNISQLE-----LQKRSLEVTVWDYDLGKSNDFIGGVTF-GMSSKGECLKHWME 365

  Fly   458 VCNSPRRQIAEWHKL-NE 474
            ..::|.::...||.| ||
 Frog   366 CLSTPNKRTEHWHTLTNE 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	48/147 (33%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	54/141 (38%)
doc2a	XP_031748920.1	C2A_Rabphilin_Doc2	86..209	CDD:176000	47/137 (34%)
		C2	248..380	CDD:472691	51/137 (37%)