Protein Alignment Syt4 and doc2b

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002934390.1
• Gene: doc2b / 100496262
• XenbaseID: XB-GENE-6032690
• Length: 394
• Species: Xenopus tropicalis
• Alignment Length: 435
• Identity: 121/435 - (27%)
• Similarity: 189/435 - (43%)
• Gaps: 97/435 - (22%)

  Fly    53 FPFQPTRRPTAVRSPSGQPPHYLKKSPSPTGGKQMGLLSPMQDQSTSPIAQPNV-----KYSEEG 112
            ||..|...|.||...:....:..:.|.||.              .||...:.:|     .|....
 Frog    36 FPRFPRGIPAAVTRANSLKSNVSQPSVSPC--------------ETSKEEEEDVDKLFGAYGAAS 86

  Fly   113 DGPAQHAEQQNGNQLTVVDGNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNGKELTVTDQY 177
            ..||:|.|:.:                                    ||.:.         :|..
 Frog    87 TAPAKHEEEGD------------------------------------LDGYD---------SDDC 106

  Fly   178 GKLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLP-- 240
            ..|||:.|.|.|..|.|||..:|.:.:||.           |...||    .:||||||.|||
 Frog   107 TTLGTLDFSLLYDQENNALHCTINKAKGLK-----------PMDHNG----LSDPYVKLHLLPGA 156

  Fly   241 DKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIE 305
            .|.:|::|:.:|||.||.::|..|:||:...|:...:|...:...|::..::.|||...||..::
 Frog   157 SKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRIPLKKLK 221

  Fly   306 IGDISKEALSISKEI-----QPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTG 365
            .......::.:.|::     :.:||    :.||.:||||.:......|.|.:::..:|..||..|
 Frog   222 PNQTKNFSICLEKQLPIDKTEDKSL----EERGRILISLKYSSQKSGLLVGIIRCAHLAAMDANG 282

  Fly   366 LADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDR 430
            .:|||||.||..:..:.:|.||.|||:||:|.|||.|.::|..::     |...:||:.:.|:|.
 Frog   283 YSDPYVKTYLKPDEDKKSKHKTAVKKKTLNPEFNEEFCYEIKHSD-----LAKKTLEVTVWDYDI 342

  Fly   431 VTKNEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHKL-NE 474
            ...|:.||.:.| |.|:....|.||.:...:..::|..||.| ||
 Frog   343 GKSNDFIGGVVL-GINAKGERLKHWFDCLKNKDKKIERWHTLTNE 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	46/149 (31%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	51/141 (36%)
doc2b	XP_002934390.1	C2A_Rabphilin_Doc2	109..232	CDD:176000	45/137 (33%)
		C2B_Rabphilin_Doc2	251..383	CDD:176030	48/137 (35%)