Protein Alignment Syt4 and syt6

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002935822.2
• Gene: syt6 / 100488667
• XenbaseID: XB-GENE-953252
• Length: 528
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 164/506 - (32%)
• Similarity: 244/506 - (48%)
• Gaps: 98/506 - (19%)

  Fly     7 PDASV-MDTIVPAILGLTAAAVLSSVACICARQMRL-----RNKKQSQHDASFPFQPTRRPTAVR 65
            ||.|| :..::..:.||...||...:.      .:|     |||       :.|..|..:..|
 Frog    53 PDLSVSLLAVIVIVCGLALVAVFLFLF------WKLWWVPWRNK-------AVPSNPAEKQNA-- 102

  Fly    66 SPSGQPPHYLKKSPSPTG---GKQMGLLSPMQDQSTSPIAQPNVKYSEEG-DGPAQ--------- 117
                         .|.||   .|: .:...::|.|.....:..||.|... |.||:
 Frog   103 -------------SSVTGINCDKE-AMADKLKDASNLGFLEAAVKISHTSPDIPAEVQMSMKEHL 153

  Fly   118 ----HAEQQNGNQLTVVDGNGLKHSLHNSLHHSPVETIANGSVTITLDDHSLTNG-------KEL 171
                ..::|.....:.......|..|:..:|   |.::..|:.|:.:.:...:.|       |:.
 Frog   154 MRRTRIQRQTTEPASSTRHTSFKRHLNRQMH---VCSVDFGTDTLQVTEQPTSIGRIKPELYKQK 215

  Fly   172 TV------TDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPCKG--GSSGTGDIPTGMNGRTQA 228
            :|      .|.....|.|.|.|:|..|...|:|.|::...||.|.  |||
 Frog   216 SVDSEDIKKDDAKTCGKINFTLKYDYEIETLIVRILKAFDLPAKDFCGSS--------------- 265

  Fly   229 ATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDV 293
              |||||:.||||::.|.:|||.|.|.||.:||.|.| .:..:||.|..||..:..|||:||.|:
 Frog   266 --DPYVKIYLLPDRKRKFQTRVHRKTLNPTFDESFHF-PVPYDDLPNRKLHLSVFDFDRFSRHDM 327

  Fly   294 IGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNL 358
            ||||:.. ...|..|:|:|: ||.|:||..:.:  :...||::.|||:.|.|||||:.::|.|||
 Frog   328 IGEVILE-NLFEESDLSRES-SIWKDIQYATTE--SVDLGEIMFSLCYLPTAGRLTLTVIKCRNL 388

  Fly   359 PRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLEL 423
            ..||:||.:|||||:.||.:|:|:.||||.:||.||:|.:||:..||||.     .:::.|||.:
 Frog   389 KAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPTYNEAIIFDIPP-----ENMDQVSLLI 448

  Fly   424 MLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHKLNE 474
            .::|:|||..||:||...:|. ::.....:||||:...||:.|..||.|.|
 Frog   449 SVMDYDRVGHNEIIGVCRVGN-STEGLGRDHWNEMLAYPRKPITHWHPLVE 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	59/144 (41%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	64/140 (46%)
syt6	XP_002935822.2	COG5038	<90..>331	CDD:227371	76/284 (27%)
		C2A_Synaptotagmin-1-5-6-9-10	229..354	CDD:176031	59/144 (41%)
		C2B_Synaptotagmin-3-5-6-9-10	363..496	CDD:176048	64/138 (46%)