Protein Alignment Syt4 and LOC100486361

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002931826.4
• Gene: LOC100486361 / 100486361
• XenbaseID: XB-GENE-29078307
• Length: 959
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 122/553 - (22%)
• Similarity: 207/553 - (37%)
• Gaps: 175/553 - (31%)

  Fly    42 RNKKQSQHDASFPFQPTRRPTAVR--------SPSGQPPHYLKKSPSPTGGKQMGLLSPMQDQST 98
            |:.|:|:       .|.|.|:..:        ||..:.|:.          .|:...| .:::|.
 Frog   440 RSSKRSK-------LPVRLPSVSKETKVDVPLSPRDKLPNV----------SQLETAS-CKEESV 486

  Fly    99 SPIAQPNVK---YS-------------EEG-----------DGPAQHA--EQQNGNQLTVVDGN- 133
            :|..:|.||   ||             |:|           :...:||  |.::|..|   |||
 Frog   487 TPEIKPEVKGTPYSNVQILIDTVTSDEEQGATASVKAAQRSEDVVEHATCESEDGKSL---DGNV 548

  Fly   134 ---------GL--KHSLHN------------SLHH-------------------SPVETIANGSV 156
                     |:  ..||.|            :|.|                   |..|:.....:
 Frog   549 DSNPTSQAIGVTSARSLVNIYTSTETYNKPQTLSHQLLEPERAKELSRSTPALLSETESDTASEI 613

  Fly   157 TITLDDHSLTNGKELTVTD-----------------QYGKL---GTIYFKLRYLAERNALMVSII 201
            :..|..|..|:..:...:|                 .:|.:   |.:.|.|.|..:.....:|:.
 Frog   614 SFQLKRHRKTHSSDSNSSDMASVSSVSNSVLSVYSGDFGSVDAQGAVEFSLDYDEKNREFQISVS 678

  Fly   202 RCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQH--KVKTRVVRNTRNPVYDEDFT 264
            :|:.|.          |.....||    :|||||..|||||..  |.||.|.|.|.||||:|...
 Frog   679 QCKDLA----------IVDEKKGR----SDPYVKTYLLPDKARMGKRKTSVKRRTTNPVYNEVLR 729

  Fly   265 FYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEIGDISKEALSISKEIQPRSLKIR- 328
             |.:....|....|:..:...|...|:..:||:...|||.:..:..    |....::|||:...
 Frog   730 -YKIEKMVLLIQKLNLSVWHNDPLGRNSFLGEMEIDLTSWDWSNTK----SNWYPLKPRSVSAMN 789

  Fly   329 -AQGRGELLISLCW---------QPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIA 383
             ....|.:.:|:.:         .|.:|.:.:.:...::||::..:|: |.:||.|:|.:..:.:
 Frog   790 GVDHLGVMNLSIKYIPPGSLGPKHPTSGEVHIWVKDTKDLPQLRPSGV-DSFVKCYVLPDTSKKS 853

  Fly   384 KKKTHVKKRTLSPVFNESFAFDIPAAEGAGASLEGVSLELMLLDWDRVTKNEVIGRLELG----- 443
            .:||.|.|:..:||||.:..:|....|    .|....:||.:.|.:::: |..:|.:.||
 Frog   854 YQKTRVIKKDSNPVFNHTIVYDGFHTE----DLRDACVELTVWDHEKLS-NHFLGGIRLGLGTGF 913

  Fly   444 -------GPNSSSTALNHWNEVCNSPRRQIAEW 469
                   ..:|:...:..|.|:.::|.    ||
 Frog   914 SYGIAVDWMDSTQEEVAFWQEMMSTPN----EW 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	42/147 (29%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	36/159 (23%)
LOC100486361	XP_002931826.4	PHD_SF	13..>68	CDD:473978
		C2A_SLP-1_2	657..781	CDD:176039	42/142 (30%)
		C2B_SLP_1-2-3-4	795..950	CDD:175987	36/158 (23%)