Protein Alignment Syt4 and syt1

DIOPT Version :10

• Sequence 1: NP_477464.1
• Gene: Syt4 / 40876
• FlyBaseID: FBgn0028400
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_017947750.1
• Gene: syt1 / 100037879
• XenbaseID: XB-GENE-5752629
• Length: 425
• Species: Xenopus tropicalis
• Alignment Length: 323
• Identity: 128/323 - (39%)
• Similarity: 197/323 - (60%)
• Gaps: 46/323 - (14%)

  Fly   161 DDHS---LTNGKELTVTDQYGKLGTIYFKLRYLAERNALMVSIIRCRGLPC--KGGSSGTGDIPT 220
            ||.:   ||:|::.....:..|||.:.:.|.|..:.|.|||.||:...||.  .||:|
 Frog   124 DDDAETGLTDGEDKEQPKEVEKLGKLQYSLDYDFQNNQLMVGIIQAAELPALDMGGTS------- 181

  Fly   221 GMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTF---YGLNMNDLQNMSLHFVI 282
                      ||||||.|:|||:.|.:|:|.|.|.|||::|.|||   |.    :|...:|...:
 Frog   182 ----------DPYVKLFLMPDKKKKFETKVHRKTLNPVFNEQFTFKVPYA----ELGGKTLVLTV 232

  Fly   283 LSFDRYSRDDVIGEVVCPLTSIEIGDISKE---ALSISKEIQPRSLKIRAQGRGELLISLCWQPA 344
            ..|||:|:.||||:|..|:.:::.|.:::|   .:|..||.|.:        .|::..||.:.|.
 Frog   233 YDFDRFSKHDVIGDVKVPMNTVDFGHVTEEWRDLVSAEKEEQEK--------LGDICFSLRYVPT 289

  Fly   345 AGRLTVVLLKARNLPRMDVTGLADPYVKIYLLYNGQRIAKKKTHVKKRTLSPVFNESFAFDIPAA 409
            ||:||||:|:|:||.:|||.||:||||||:|:.||:|:.||||.:||.||:|.:||||:|::|..
 Frog   290 AGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 354

  Fly   410 EGAGASLEGVSLELMLLDWDRVTKNEVIGRLELGGPNSSSTALNHWNEVCNSPRRQIAEWHKL 472
            :     ::.|.:.:.:||:|::.||:.||::.: |.||:...|.||:::..:|||.||:||.|
 Frog   355 Q-----IQKVQVVVTVLDYDKIGKNDAIGKVFV-GYNSTGAELRHWSDMLANPRRPIAQWHTL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt4	NP_477464.1	C2A_Synaptotagmin-4-11	179..322	CDD:176034	56/150 (37%)
		C2B_Synaptotagmin-4	332..473	CDD:176049	66/141 (47%)
syt1	XP_017947750.1	Syt1_N	6..114	CDD:409248
		C2A_Synaptotagmin-1-5-6-9-10	145..268	CDD:176031	53/143 (37%)
		C2B_Synaptotagmin-1	277..412	CDD:176047	66/141 (47%)