DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gld and AT1G14190

DIOPT Version :9

Sequence 1:	NP_001350861.1	Gene:	Gld / 40875	FlyBaseID:	FBgn0001112	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001321001.1	Gene:	AT1G14190 / 837979	AraportID:	AT1G14190	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	608	Identity:	152/608 - (25%)
Similarity:	265/608 - (43%)	Gaps:	136/608 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SAFMLFMGLLEVFIR-SQ--------CDLEDPCGRASSRFRSEPDYEYDFIVIGGGSAGSVVASR 82
            |.|:|.. ::..||. ||        .|.::..|::           :|:||:|||:||..:|:.
plant     2 SRFVLLF-IISTFINLSQGAQMPYMTTDAKEVSGKS-----------FDYIVVGGGTAGCSLAAT 54

  Fly    83 LSEVPQWKVLLIEAGGD---EPVGAQIPSMFLNFIGSDIDYRYNTEPEPMACLSSMEQRCYWPRG 144
            |||  ::.||:||.||.   :|:..:......:.:.:|   .|::..:....:..:|..    ||
plant    55 LSE--KYSVLVIERGGSPFGDPLVEERKYFGYSLLNTD---EYSSVAQSFTSVDGIENY----RG 110

  Fly   145 KVLGGTSVLNGMMYVRGNREDYDDWAADGNPGWAYNDVLPFFKKSEDNLDLDEVGTEYHA--KGG 207
            :||||:|.:||..|.|.:    |::..  ..||....|...:|..|..:......|::.:  :.|
plant   111 RVLGGSSAINGGFYSRAS----DEFVK--KAGWDKGLVQESYKWVESKVVFMPELTQWQSVVQFG 169

  Fly   208 LLPVGKFPYNPPLSYAILKA-GEELGFSVHDLNGQNSTGFMIAQMTARNGIRYSSA--RAFLRPA 269
            .|..|.:|||   .|::... |.::|.|::|..|:                |::||  ..|.:|
plant   170 FLEAGFYPYN---GYSLEHTQGTKIGGSIYDQCGK----------------RHTSADLLGFGKP- 214

  Fly   270 RMRNNLHILLNTTATKILIHPHTK-NVLGVEVSDQFGSTR---KILVKK---EVVLSAGAVNSPH 327
               |.:.:|||||...|:.....| ..:||...:..|::.   |:.|::   ||:|:|||:.||.
plant   215 ---NCITVLLNTTVKSIIFDSSNKTRAVGVRFMESDGNSSKSYKVHVEQHRGEVILAAGALGSPQ 276

  Fly   328 ILLLSGVGPKDELQQVNVRTVHNLPGVGKNLHNH--VTYFTNFFIDDADTAPLNWATAMEYLLFR 390
            ||||||:||::.|:..::..:.||..||:.:.::  ::...:.|..:....|...|...|...|.
plant   277 ILLLSGIGPENHLKDFDIPVIVNLKEVGRKMSDNPAISLLVDRFSQNRTLEPPQVAAIAEGYKFI 341

  Fly   391 DGLMSGTGISDVTAKLATRYADSPERPDLQLYFGGYLASCARTGQVGELLSNNSRSIQIFPAVLN 455
              |.|....:|:|   .||                                     |.|...:..
plant   342 --LESEVLPTDIT---TTR-------------------------------------ISIAAKIAF 364

  Fly   456 PRSRGFIGLRSADPLEPPRIVANYLTHEQDVKTLVEGIKFVIRLSQTTPLKQYGMRLDKTVVKGC 520
            |:|:|.:.|.|.:|.|.|.:..|||.::.|:...:|.:..:..::::..:         |...|.
plant   365 PKSKGRLKLNSTNPRENPSVKFNYLENKADLDACLEMVLHLQHVARSETV---------TFFLGT 420

  Fly   521 EAH--AFGSDAYWECAVRQNTGPENHQAGSCKMGPSHDPMAVVNHELRVHGIRGLRVMDTSIMPK 583
            :||  ....|...:....:|.....|..|.|.:|      :||:.|.:|:|::.|||:|.|...:
plant   421 QAHDKLVAGDEELKSFCIKNVRTYYHYHGGCVVG------SVVDEEYKVNGVKRLRVVDGSTFEE 479

  Fly   584 VSSGNTHAPAVMIAE-KGAYLLK 605
            ....|..|..:|:.. :|..:||
plant   480 SPGTNPMATVLMLGRYQGIKILK 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gld	NP_001350861.1	Pyr_redox_dim	29..>95	CDD:332164	22/74 (30%)
Gld	NP_001350861.1	GMC_oxred_C	64..601	CDD:331873	140/556 (25%)
AT1G14190	NP_001321001.1	PLN02785	36..504	CDD:215420	143/573 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.830