DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gld and AT5G51930

DIOPT Version :9

Sequence 1:	NP_001350861.1	Gene:	Gld / 40875	FlyBaseID:	FBgn0001112	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_200006.1	Gene:	AT5G51930 / 835268	AraportID:	AT5G51930	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	623	Identity:	156/623 - (25%)
Similarity:	248/623 - (39%)	Gaps:	142/623 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SAFMLFMGLLEVFIRSQCDLEDPCGRASSRFRSEPDYEYDFIVIGGGSAGSVVASRLSEVPQWKV 91
            |.|..|:..||........|            :..:..:|:|:||||:||..:|:.||:  ...|
plant    47 SIFFFFLVKLETTFMKDATL------------APKNASFDYIIIGGGTAGCALAATLSQ--NASV 97

  Fly    92 LLIEAGG---DEPVGAQIPSMFLNFIGSDIDYRYNTEPEPMACLSSMEQRCYWPRGKVLGGTSVL 153
            |::|.||   :.|....        :|:.::...|..|...:.|...|...|..|.:||||.||:
plant    98 LVLERGGSPYENPTATD--------MGNSVNTLLNNTPNSWSQLFISEDGVYNTRPRVLGGGSVI 154

  Fly   154 NGMMYVR-GNREDYDDWAADGNPGWAYNDVLPFFKKSEDNLDLDEVGTEYHA--KGGLLPVGKFP 215
            ||..|.| ||  ||.:.|.     |...:|...::..|..|..:....|:..  |.|||..|:.|
plant   155 NGGFYSRAGN--DYVEEAE-----WEMEEVEAAYEWVEKKLVFEPQVIEWQKAFKDGLLEAGESP 212

  Fly   216 YNPPLSYAILKAGEELGFSVHDLNGQNSTGFMIAQMTARNGIRYSSARAFLRPARMRNNLHILLN 280
            .| ..:|..: .|.::|.::.|..|.        :.||.|.:.|::.          |.:.:.|:
plant   213 DN-GFTYDHI-YGTKIGGTIFDRAGH--------RHTAANLLEYANP----------NRIVVYLH 257

  Fly   281 TTATKILIHPHTKNVLGVEVSDQFGSTRKILVKK---EVVLSAGAVNSPHILLLSGVGPKDELQQ 342
            .:..|:|.......||..:.:..|....  |..|   ||:|||||:.||.:|:||||||...|:.
plant   258 ASVHKVLFTTEAYEVLFEDANGVFHKAN--LANKATNEVILSAGALGSPQLLMLSGVGPAVHLEA 320

  Fly   343 VNVR-TVHNLPGVGKNLHNHVTYFTNFFIDDADTAPLNWATAM---EYLLFRDGLMSGTGIS-DV 402
            ..|. .|.:.|.||:.:.::...|.  .|.......|:...|:   ::..:.:|| ||..:| |:
plant   321 HGVNPLVLDQPMVGQGMADNPMNFV--AIPSPQPVELSLIQAVGITKFDSYIEGL-SGLSLSFDI 382

  Fly   403 TAKLATRYADSPERPDLQLYFGGYLASCARTG----------QVGELLSNNSRSIQ-------IF 450
            |.:                :|.|.|.....|.          .:..||.:....::       ||
plant   383 TRR----------------FFDGVLNLLNETSHTTSRKILTQSIAVLLKSFDVKLEVRMNGGLIF 431

  Fly   451 PAVLNPRSRGFIGLRSADPLEPPRIVANYLTHEQDVKTLVEGIKFVIRLSQTTPLKQY------- 508
            ..|..|.|:|.:.||:.:|.:.|.:..||....:|:...|:|:..:||:..:....:|
plant   432 QKVDGPASKGHMKLRNTNPRDNPSVTFNYYQEPEDLNKCVKGLNTIIRMINSKAFSKYKYPGVTA 496

  Fly   509 ------------GMRLDKTVVKGCEAHAFGSD---AYWECAVRQNTGPENHQAGSCKMGPSHDPM 558
                        .:| .:.|........|..|   :.|            |..|.|::|
plant   497 RELLNLMLALPINLR-PRHVTSAFNLKQFCIDTVTSVW------------HYHGGCQVG------ 542

  Fly   559 AVVNHELRVHGIRGLRVMDTSIMPKVSSGNTHAPAVMI 596
            .||:...:|.||.||||:|.|...|....|..|..:|:
plant   543 KVVDKNYKVLGIDGLRVIDGSTFLKSPGTNPQATVMML 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gld	NP_001350861.1	Pyr_redox_dim	29..>95	CDD:332164	18/65 (28%)
Gld	NP_001350861.1	GMC_oxred_C	64..601	CDD:331873	150/586 (26%)
AT5G51930	NP_200006.1	BetA	70..582	CDD:225186	150/588 (26%)
		NADB_Rossmann	73..317	CDD:304358	85/282 (30%)
		GMC_oxred_C	437..581	CDD:282984	39/163 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H81411
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730