DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10050 and dtwd2

DIOPT Version :9

Sequence 1:	NP_649713.1	Gene:	CG10050 / 40873	FlyBaseID:	FBgn0037492	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001016607.1	Gene:	dtwd2 / 549361	XenbaseID:	XB-GENE-5735070	Length:	276	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	105/235 - (44%)
Similarity:	140/235 - (59%)	Gaps:	7/235 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GISADP----PNRRNKCEKCKRPVVVCWCPALPHPPEAVSSQIVILQHPAEEKRSLRTALMLQLG 71
            |:||.|    .:||..|.:|.||..||.||.||..|..||:.:.|:||||||.|.|||..:|...
Frog    31 GLSALPVENSTDRRALCARCSRPQKVCLCPFLPVCPLDVSTSLYIVQHPAEEGRVLRTVPLLAAC 95

  Fly    72 LEPGKCVVYKGKRFPNHRNHADLQRILDSPQTLLLYPSRDSVPLEEVDHS--AGPYTLVLIDGTW 134
            |...||.|..|:||...| :.:|..:..:|.|.:|||..::..|||:..:  ..||.|::|||||
Frog    96 LPHEKCKVLIGRRFGEER-YPELATVCRNPGTFILYPGAEAANLEEMSLADIQPPYALIIIDGTW 159

  Fly   135 PQAKAIYASSPALHRLRQVKLIAVGISDYIIRTQPTEGCLSTLETAAQCLAVLESRPELRQTLVR 199
            .|||.|:..:......:||:|.....|.|:||||||..||||||.||..|:|:|.|.|:::.::|
Frog   160 SQAKDIFYKNTLFRLPKQVQLKTPISSQYVIRTQPTNMCLSTLECAAAALSVMEKRTEIQEIILR 224

  Fly   200 PLHTLCKYQLDNGAVEHQSKEFLLKNNQYPKPIGKRLSRL 239
            ||..||.:||.:||..|.|||.|||...|.||:.|...:|
Frog   225 PLQALCSFQLQHGAQIHHSKEHLLKTGLYNKPMPKNKRKL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10050	NP_649713.1	DTW	20..209	CDD:281875	84/190 (44%)
dtwd2	NP_001016607.1	DTW	44..230	CDD:377168	82/186 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4156
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H79701
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3822
OMA	1	1.010	-	-		QHG58133
OrthoDB	1	1.010	-	-		D429011at33208
OrthoFinder	1	1.000	-	-		FOG0005667
OrthoInspector	1	1.000	-	-		oto104477
Panther	1	1.100	-	-	LDO	PTHR21392
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10123
SonicParanoid	1	1.000	-	-		X6102
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110