Protein Alignment CG10050 and DTWD2

DIOPT Version :9

• Sequence 1: NP_649713.1
• Gene: CG10050 / 40873
• FlyBaseID: FBgn0037492
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: XP_011541640.3
• Gene: DTWD2 / 285605
• HGNCID: 19334
• Length: 318
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 110/269 - (40%)
• Similarity: 146/269 - (54%)
• Gaps: 28/269 - (10%)

  Fly     2 EDDAWLDLVGISADPPNRRNKCEKCKRPVVVCWCPALPHPPEAVSSQIVILQHPAEEKRSLRTAL 66
            :||:...|..:..:|..||.:|.:|.||..||.||.||..|..:|:.:.|:||||||.:.|||..
Human    48 DDDSADGLWELPVEPAERRPECTRCSRPQKVCLCPFLPAHPLHISTHLYIIQHPAEENKVLRTVP 112

  Fly    67 MLQLGLEPGKCVVYKGKRFPNHRNHADLQRILDSPQTLLLYPSRDSVPLEE--VDHSAGPYTLVL 129
            :|...|...||.|..|:||...|: .:|..:.....||:|||..::..|||  :|....|.|:::
Human   113 LLAACLPQDKCKVKIGRRFSEERD-PELSTVCRKSGTLILYPGAEAANLEEFILDSPVYPSTIII 176

  Fly   130 IDGTWPQAKAIY------------------ASSPALHR--LRQVKLIAVGISDYIIRTQPTEGCL 174
            |||||.|||.|:                  |...||.|  ..||:|.....|.|:||.|||..||
Human   177 IDGTWSQAKDIFYKNSLFRHPKQQEDFHLQARKRALTRTVTMQVQLKTSISSQYVIRMQPTNRCL 241

  Fly   175 STLETAAQCLAVLESRPELRQTLVRPLHTLCKYQLDNGAVEHQSKEFLLKNNQYPKPIGK----- 234
            ||||.||..|::||....:::||:|||..||.:||.:||....|||.||||..||||:.|
Human   242 STLECAAVALSILEKNNYIQETLLRPLQALCSFQLQHGAQIRLSKEHLLKNGLYPKPMPKNKRKL 306

  Fly   235 RLSRLLRNT 243
            |...||.|:
Human   307 RKMELLMNS 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10050	NP_649713.1	DTW	20..209	CDD:281875	85/210 (40%)
DTWD2	XP_011541640.3	DTW	66..276	CDD:309167	85/210 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143396
Domainoid	1	1.000	154	1.000	Domainoid score	I4267
eggNOG	1	0.900	-	-		E1_COG3148
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H79701
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3913
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58133
OrthoDB	1	1.010	-	-		D429011at33208
OrthoFinder	1	1.000	-	-		FOG0005667
OrthoInspector	1	1.000	-	-		oto90685
orthoMCL	1	0.900	-	-		OOG6_105506
Panther	1	1.100	-	-	LDO	PTHR21392
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10123
SonicParanoid	1	1.000	-	-		X6102
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800