DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1227 and stk16

DIOPT Version :9

Sequence 1:	NP_001287207.1	Gene:	CG1227 / 40872	FlyBaseID:	FBgn0037491	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001004792.1	Gene:	stk16 / 448012	XenbaseID:	XB-GENE-971765	Length:	305	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	121/312 - (38%)
Similarity:	182/312 - (58%)	Gaps:	19/312 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIE 77
            |.|..|.:.::.|...||....:|..||||.:||.|.....|.||:|||.||..:|:..|..|:|
Frog     3 GALCICSRGSITIENKRYFFVHKLGEGGFSYVDLVEGVQDGRFYALKRILCHDREDRKEAQHEVE 67

  Fly    78 NCRKIDSENVIRVVDYEL-----KGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPE 137
            ..|..:..||:.:|.:.:     |.:|          :::||:.|.|:|.:.:::...:...:.|
Frog    68 MHRLFNHPNVLPLVAHSIIEKGPKWEA----------WLLLPFVKGGTLWNQVEVLRDRNSFLSE 122

  Fly   138 AQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQ 202
            .:|:.|..|:|.||||||:.   ..||||||..|:.|.|...|:::|||||.:||:::.....|.
Frog   123 DRIVHILHGICLGLKAIHDR---GYAHRDLKPTNVLLEDDDRPLLMDLGSMNQARMEVKDSRQAM 184

  Fly   203 RLQDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAV 267
            .:||.|.:|.:|.|||||||.|.:.|.||||||||||||||::|.:...|||.|:::||||||||
Frog   185 AVQDWAAQRCTISYRAPELFNVSSDCVIDERTDIWSLGCVLFSMMFGEGPYDMIFQKGDSVALAV 249

  Fly   268 LSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDLIQKLEGR 319
             ..||.:|.:..|::.:..|:..|:..:..||||:.::|.....|...:||:
Frog   250 -QNNITVPANERYSQGLQTLLCSMMVVNSQERPFISTIISHVEALQPIVEGQ 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1227	NP_001287207.1	STKc_16	29..314	CDD:270888	115/289 (40%)
CG1227	NP_001287207.1	S_TKc	30..300	CDD:214567	109/274 (40%)
stk16	NP_001004792.1	STKc_16	19..295	CDD:270888	115/289 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	209	1.000	Domainoid score	I2788
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2739
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3424
OMA	1	1.010	-	-		QHG53761
OrthoDB	1	1.010	-	-		D442669at33208
OrthoFinder	1	1.000	-	-		FOG0005637
OrthoInspector	1	1.000	-	-		oto103194
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R967
SonicParanoid	1	1.000	-	-		X4038
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010