DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10053 and gpatch11

DIOPT Version :9

Sequence 1:	NP_001287206.1	Gene:	CG10053 / 40871	FlyBaseID:	FBgn0037490	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001005035.1	Gene:	gpatch11 / 448554	XenbaseID:	XB-GENE-5921609	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	104/273 - (38%)
Similarity:	151/273 - (55%)	Gaps:	20/273 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDEEEDYMSDKFLVGLQDVRPSLVHNRGRKRQIEVESKKDE--LKKRQRETAASSGNVDNVRLQ 63
            |.:||||||||.|:..||||||.:...|..|...|.|.|..|  :|.||::..    :|:..:..
Frog     1 MEEEEEDYMSDAFINSLQDVRPGMSMPRRVKECYEKEEKHKEANIKNRQQKLK----DVEKEKRD 61

  Fly    64 QSLNKPISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGRE-----AAVAELA 123
            ..||:.:..:||||.||.|||||.|..||...|...||:.:.||:||.|:|.|     .|...|.
Frog    62 TKLNEALGNENKGFALLQKMGYKKGQALGKKGDGIVEPIPLNIKTGRSGIGHEEMKKRKAEENLE 126

  Fly   124 LKRQKLRRAHLLNKAGIKSDEEVSTEAYRRRATHKAEERKLQYDIKRCQQTCESLDLKSAITEPD 188
            ..|:|::..        |.|||.:.:.:|.|...|.||.:|:.|:.:.|:.|..||.:.:|:.|.
Frog   127 SYRRKIQMR--------KHDEEQAADDFRMRMKSKREEIRLKADLSKSQRACMLLDGQKSISTPR 183

  Fly   189 LDFFWPPKPKDEDESQSDADDPEVEVPPKQEPYSPSEQLELLTGYLRTAYCFCYWCGTHYDDAED 253
            ..::||...:.|.:.::| ::.|.:....:|..|..|:|::||.|||..:.||.||||.|.|.||
Frog   184 EAWYWPKMNEQEADEEAD-EETEEDEDLVEEELSTLEKLQILTSYLRGRHLFCIWCGTTYQDDED 247

  Fly   254 LGSNCPGLTRDEH 266
            :.|||||.|.::|
Frog   248 MESNCPGDTAEDH 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10053	NP_001287206.1	G-patch	73..116	CDD:279867	23/42 (55%)
CG10053	NP_001287206.1	DUF4187	219..266	CDD:290533	25/46 (54%)
gpatch11	NP_001005035.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..67		28/69 (41%)
		G_patch	68..114	CDD:197727	23/45 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..124		13/35 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..213		5/29 (17%)
		DUF4187	215..260	CDD:372738	24/44 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10388
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44687
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3882
OMA	1	1.010	-	-		QHG59991
OrthoDB	1	1.010	-	-		D1277915at2759
OrthoFinder	1	1.000	-	-		FOG0003015
OrthoInspector	1	1.000	-	-		oto103573
Panther	1	1.100	-	-	LDO	PTHR21032
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1808
SonicParanoid	1	1.000	-	-		X4461
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110