DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10053 and Gpatch11

DIOPT Version :9

Sequence 1:	NP_001287206.1	Gene:	CG10053 / 40871	FlyBaseID:	FBgn0037490	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001102170.1	Gene:	Gpatch11 / 362685	RGDID:	1311424	Length:	260	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	98/274 - (35%)
Similarity:	152/274 - (55%)	Gaps:	28/274 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EEEDYMSDKFLVGLQDVRPSL-----VHNRGRK----RQIEVESKKDELKKRQRETAASSGNVDN 59
            ||||||||.|:...:||||.:     :....||    :|..:::::..||:.:||
  Rat     3 EEEDYMSDSFINVQEDVRPGVPMLRQIREARRKEEKQQQANLKNRQKSLKEEERE---------- 57

  Fly    60 VRLQQSLNKPISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGREAAVAELAL 124
             |....|...:..:||||.||.|||||:|..||.|.|...||:.:.:|:|:.|:|.|:.:...|.
  Rat    58 -RRDIGLKNALGCENKGFALLQKMGYKSGQALGKTGDGIVEPIPLNVKTGKSGIGHESLLKRKAE 121

  Fly   125 KRQK--LRRAHLLNKAGIKSDEEVSTEAYRRRATHKAEERKLQYDIKRCQQTCESLDLKSAITEP 187
            :|.:  .|:.|:.|:.     ||.:.|.:|.|...|.:|.:|:.|::|.|:.|:.||.:..|..|
  Rat   122 ERLESYRRKIHMKNQR-----EEKAAEEFRMRLKSKQDELRLEGDLRRSQRACQQLDAQKNIQVP 181

  Fly   188 DLDFFWPPKPKDEDESQSDADDPEVEVPPKQEPYSPSEQLELLTGYLRTAYCFCYWCGTHYDDAE 252
            ...::| .:|::|.|.:.:..:.:.|.....|..|..|:|::||||||..:.:|.||||.|:|.|
  Rat   182 REAWYW-MRPEEETEEEEEEKEEQDEDKCPSEDLSVLEKLQILTGYLREEHLYCIWCGTAYEDKE 245

  Fly   253 DLGSNCPGLTRDEH 266
            ||.|||||.|..:|
  Rat   246 DLSSNCPGPTSADH 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10053	NP_001287206.1	G-patch	73..116	CDD:279867	22/42 (52%)
CG10053	NP_001287206.1	DUF4187	219..266	CDD:290533	26/46 (57%)
Gpatch11	NP_001102170.1	G-patch	70..113	CDD:396249	22/42 (52%)
Gpatch11	NP_001102170.1	DUF4187	212..259	CDD:404667	26/46 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341812
Domainoid	1	1.000	64	1.000	Domainoid score	I9980
eggNOG	1	0.900	-	-		E1_KOG1994
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44687
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3954
OMA	1	1.010	-	-		QHG59991
OrthoDB	1	1.010	-	-		D1277915at2759
OrthoFinder	1	1.000	-	-		FOG0003015
OrthoInspector	1	1.000	-	-		oto96877
orthoMCL	1	0.900	-	-		OOG6_105065
Panther	1	1.100	-	-	LDO	PTHR21032
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4461
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770