DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1234 and AT1G79150

DIOPT Version :9

Sequence 1:	NP_649710.1	Gene:	CG1234 / 40870	FlyBaseID:	FBgn0037489	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_178036.2	Gene:	AT1G79150 / 844256	AraportID:	AT1G79150	Length:	830	Species:	Arabidopsis thaliana

Alignment Length:	858	Identity:	206/858 - (24%)
Similarity:	362/858 - (42%)	Gaps:	183/858 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 DPLEEDNEDGDDEM---LENV--ADMLDGDDLALLQANKRKRKAKTTGENDPDQGQSIGLERAYA 134
            |..|||.|..|:::   .||.  |..:...|.|.:.        |..|      |:.:.:|..|.
plant    19 DVAEEDIEFSDEDLKYVKENTDYAQFVSQIDTAAIN--------KQCG------GRVMTVEDKYE 69

  Fly   135 SDTKKEQDAQKIK---------LDLLPIKSRDGQIITRTTEVDYIPKPKQKKKNEEEEEDDSEED 190
            .:..|.:..|:.|         :|:||:|:.||::..||        ..:|.|..|.|.|::|:|
plant    70 EERSKRKTLQEEKGNGEILVDPVDVLPVKTLDGKLHYRT--------ESKKSKLAEAETDEAEKD 126

  Fly   191 -----------------------GDTEYEDSDDDVVNDVE----AATAAPVQKLISTTDLLIARQ 228
                                   .....:|..|:::.:.|    ||..|.|::.:|.       :
plant   127 VLEDEHVLNKSQRREKAKKSKREAKKHEKDLPDEILQEEEETPQAAVLAEVKEELSA-------E 184

  Fly   229 QEIERQKYRIGIICSGLLEKPEDKMRNFHALYELMDEINPASRQANLMAVRKLAIISVTEIFKDI 293
            :..|.:|.:|..:...||..||   .|...|.:::|    ..:..|...| |||::|:..:||||
plant   185 ESFENKKNKIAELGMLLLSDPE---ANIKTLKDMLD----ICKDQNTKIV-KLALLSLLAVFKDI 241

  Fly   294 LPEYRV---GQVDTKMQTLRKATLDRVTFENALLQQFKKFLQKL-----EQITAQVNRRGGLRTP 350
            :|.||:   .:.:.:|:..::....|. :|:.||:.:|.:||||     :.:..|:..|
plant   242 IPGYRIRLPTEKELEMKISKEVKKTRF-YESTLLKAYKSYLQKLIIFEKQSVYNQIANR------ 299

  Fly   351 QTVKLATVAVQCMCDLLVAHPYFNYVQNIAQLLVYMLNCNYAEMRTAVHQCFRTVFSNDKRL--E 413
                       |:|.||.|.|:|||..|:...:|..::.....:|.......|.:|||:.:.  |
plant   300 -----------CLCTLLEAVPHFNYRDNLLIAVVRNISSPDEVVRRLCCSTIRYLFSNEGKHGGE 353

  Fly   414 MTLFIVRRINHLIKTKQNNVHVECITCLMGLK----IKNVNLDAEKENELKQKKLESHRQRLLSL 474
            :|:..||.|...:|.....:|...|...|.::    |...|.:.|...:.|:......::....:
plant   354 LTVQAVRLIADHVKAHNCQLHPNAIEVFMSIRFDEDIGKPNKEDEHNKKYKKNNKRKTQEEQNQV 418

  Fly   475 SKKERKRRKK------LTEVNRELEETRAEENKQAKHQKLTEIIKMVFTIYFRVLKND------- 526
            .:.|||:.||      ..||:.:......|.:.:.:.:..||.:..||..|||:|:|.
plant   419 QENERKKSKKDMMSKIRDEVSADHRGVTYEPDAKERRKMQTETLSAVFETYFRILRNTMYTIGER 483

  Fly   527 ----PTSR--------VLSAILEGLAEFAHVINLDFFSDLIDVLNRILEDQDE------------ 567
                |||.        :|:..|:|||:|...::||:..||::.|.::......
plant   484 TEEIPTSNPGAFGSHPLLAPCLDGLAKFTQQLDLDYMGDLMNYLKKLASSSSSVSNNTKQKNSKL 548

  Fly   568 LGYRERLHCVQTIFVILSGQGEVLNIDPIRFYQHFYRNMLAVQAGKNHDDFAIILRTLDEVLVKR 632
            |...|||.|....|.::......||:|...|:...|..:|..:.|:   |..:||....::::..
plant   549 LTVSERLRCCLVAFKVMRSNLNALNVDLQDFFVQLYNLILEYRPGR---DSGVILAESLKIMLCD 610

  Fly   633 RRNMSQQRLMAFMKRLLTGSLHLLHNGTLATLGTIKQTFQLTSVLDNLLDTDTTIGS-----GRY 692
            .|:...|:..||:|||.|.:|......:::.|.|:|...|......|||:.|...||     .:|
plant   611 DRHQDMQKAAAFVKRLATFALCFGCAESMSALVTLKTLLQKNVKCRNLLENDAGGGSVSGSIAKY 675

  Fly   693 DPELDDPEYCNAASTALYELALLARHYHPTVRRMAVHIAHGVPATGEGALPTEIGKLTSHELFTQ 757
            .|...||....|.:|.|:||:||::||||.:..||..:::...:..:    |.:..:|..:.|..
plant   676 QPYATDPNLSGALATVLWELSLLSKHYHPAISTMATTVSNMNTSQSQ----TFLSAVTPQQAFAD 736

  Fly   758 FDSTQMAFNP--------------TIP-----LPKAGQPKL--KRGKHLYIRSDFKQEYGKLLQQ 801
            |...:.:|.|              ::|     :|:....||  |..::..|..|.|::....::
plant   737 FSLVKESFEPKNESRKLNNKRKRESLPEEAKNVPEIDMVKLSKKLKENFTILRDIKEDERVRME- 800

  Fly   802 GKVSQTKDKQTLQ 814
              :.|:::|:.|:
plant   801 --LLQSEEKKPLK 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1234	NP_649710.1	NOC3	228..727	CDD:227447	145/554 (26%)
		NOC3p	235..330	CDD:284871	28/97 (29%)
		CBF	574..727	CDD:281851	47/157 (30%)
AT1G79150	NP_178036.2	NOC3	134..714	CDD:227447	155/615 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3039
eggNOG	1	0.900	-	-		E1_COG5117
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39642
Inparanoid	1	1.050	196	1.000	Inparanoid score	I1341
OMA	1	1.010	-	-		QHG55337
OrthoDB	1	1.010	-	-		D341721at2759
OrthoFinder	1	1.000	-	-		FOG0004096
OrthoInspector	1	1.000	-	-		oto3417
orthoMCL	1	0.900	-	-		OOG6_102758
Panther	1	1.100	-	-	LDO	PTHR14428
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2841
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840