Protein Alignment thw and CG12009

DIOPT Version :10

• Sequence 1: NP_001097699.2
• Gene: thw / 40868
• FlyBaseID: FBgn0037487
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_647799.1
• Gene: CG12009 / 38405
• FlyBaseID: FBgn0035430
• Length: 905
• Species: Drosophila melanogaster
• Alignment Length: 1205
• Identity: 233/1205 - (19%)
• Similarity: 373/1205 - (30%)
• Gaps: 438/1205 - (36%)

  Fly    22 LCALIVLVI---LGYTSAESKYRTPARILAKQTGATQFEEERYEAHTNCNEHKHHLKKRASDEDV 83
            ||.|::|..   .|..||..|.:.|..           .||...|.....|     :....||:.
  Fly     5 LCLLLLLTATCSAGPLSAHQKRKAPVT-----------REEPVPAEVEMPE-----QTETEDEEA 53

  Fly    84 DYE-VYQGVVGRPGIDFPIYPRIPKTSFSCRSYGNGYFADMETDCQVFHIC-----EEGR----K 138
            ..| ...|.:..|.....|...| ..:|||.:...||:||:|.|||:||:|     .:||    :
  Fly    54 PAEAASMGTLTLPSNATSIRSDI-TDNFSCVNKTYGYYADVENDCQIFHVCLPVTYADGRENTFR 117

  Fly   139 ISFLCPNGTIFQQSELTC----DWWFKVNCLGSSGYYAESAEILNKQRVHRVRPSVPVQGFNIVG 199
            .||:||..|||.|...||    |  ..:.|..||.||..:...                     |
  Fly   118 WSFICPEETIFSQESFTCMRRED--MTIECEDSSRYYELNGNF---------------------G 159

  Fly   200 GGLNIKPKVTPVAGQGRSAAPRANPDRRIDSTEDVPASVESVDFDDVSGEKQRKVLPSIDNNSND 264
            |....:.|.|||..:        .|::  :.:|..|..|||
  Fly   160 GPAEEESKPTPVESE--------EPEK--EESEPEPEPVES------------------------ 190

  Fly   265 QESQITAESSSFVSGSGKRRTNKESNPNRNDDITVLKPARLRTPVATQERGVSTERARNGQRGQH 329
             |.:|.||                      .::...||.:   ||..|
  Fly   191 -EPEIPAE----------------------PEVQTAKPMK---PVKAQ----------------- 212

  Fly   330 RYSGSEEHSKERERPTPGQSKEKPEFFEAHSTRSVPQTTAHYSTGSHSTVRRLEPSKSTPFYTPT 394
                         :|.|.:.|.:|:       |.||           :.|......::.|  .|:
  Fly   213 -------------KPKPNRRKPQPQ-------RKVP-----------AVVTAAPEVEAIP--EPS 244

  Fly   395 VPSLVKSKSTEGKLNYIKGGHVATTPNPHRFGSASSGIFIESSVAPKVKPTASASIELDSTF--- 456
            .|..::.|..:                |.||.|.      .....|:||..|.|:..:.:..
  Fly   245 APVEMEPKPLK----------------PQRFTSR------PHQERPQVKRPAIAAPPMRNELFNG 287

  Fly   457 ---KPVIIGMRHHYDVASSGEFRPPSKSTESRDYLPTTPSPSAA----------------SSGPT 502
               :|.|..             :||:......:.:...|:.:.|                .:.|.
  Fly   288 IRKRPAIFN-------------KPPTTVKPVEEVVENEPAVTEAVVQLSEPQPTLKLQTLFAEPE 339

  Fly   503 YLPMSGKSPRVNTGGAAGEDVLLFA-PNPVKEESVFRNVQDMLKTMNLLKDQFEDVE-LNAAAAA 565
            .:|:..:.|.|.    |.|..:.|. |.||.||.|...|:        :..:.|||: :.|....
  Fly   340 VIPVEVQEPEVQ----ASEPAVTFVQPEPVVEEVVPSKVE--------IDTRIEDVKPIEAIEEI 392

  Fly   566 PARVGLEIPPSSGPDALVSFAKYFAQEHNETINSLSKKDKSEKVDKTGVQTKL--------SVKP 622
            || |.:|....|.|           ||..|......::.|.|:..|...:.||        :.||
  Fly   393 PA-VIVESLDQSRP-----------QEMQEEAKITEEEAKPEEEPKPEEEVKLEEELKSEEAAKP 445

  Fly   623 PLPTIKPSDTTALLTTSENP--PA-----ISDNADDIKKSLLSDTTVKKYS--------NLFGLK 672
            .: .:||.:..|    .|.|  ||     |..|.::||    |:..:.:.|        ||..|:
  Fly   446 EV-ELKPQEIQA----QEEPEVPAKVEEIIEANPEEIK----SEPAIMEVSNSHEEPLVNLEALE 501

  Fly   673 SAQGRGAGE-----------SDISSGLLSNQTNGTQSEAGSKYQQYPQIGSTGSTIGALAEKPET 726
            :|:...|.|           |.:...:|.|..:|...|:...::....:.:.           |.
  Fly   502 AAKPADAPESMPATPEMEQHSPLVEEILDNTNDGEAQESLGGFKPVDPVMAA-----------EA 555

  Fly   727 RKIAQIFSNALSSYLDNPATFRAELAARARPTEPPSTPNFKPVTTTDPSLFSDGTAKYYLPTKGL 791
            .::...|.|.|....:.|.|..||              :..||..||.|:   ..||  ||...:
  Fly   556 EQLITDFLNTLKKNEEKPETDLAE--------------SILPVNNTDVSI---EEAK--LPEPEI 601

  Fly   792 PDATTPTPNSIAAEINHKFDSTLAPEFSTTTELYEGS--------TNRGLEFS------------ 836
            .|........:..|...|        .|..||:.:.|        .:..:::.
  Fly   602 VDKNASVEEQLLEETEDK--------KSHKTEMMQDSPIINIMQVQHMPMDYRIPVRVIPVEVQP 658

  Fly   837 ----GELSPPSQDSGEEFLQQQQTQSFVKSRNDLLKDARPQKLVTTHKPTEHPWALKSQTDFLDP 897
                .|.|..:::|..|.:.:...:...:|..:..|::.|:::|.|     .|..:|.    :..
  Fly   659 VPAISEASEVAKESAPEVVSESSLEEAKESAAEEAKESIPEEVVDT-----APEEVKQ----IPN 714

  Fly   898 LTINDGLMKEQRTSTSSSTTSTSTTASPFAYRVTTPTPSRYEWEDIFRSYDIPRDALPSSSGLQR 962
            :.|.:..|:|.:.|            ||...:.:||       |:|       ::..|.:.....
  Fly   715 VEIQESPMEEPKES------------SPEEIKESTP-------EEI-------KETAPETEVELV 753

  Fly   963 IANKLFGGLNEQEALHLRNVMAKAEHDRQVLSLLLLLIQTCDDHNGKALERSRKHLLNALIDIDS 1027
            :|       .:|.|.|        :.|.|...:....:.:.:|                ::::
  Fly   754 VA-------PDQTAFH--------DDDAQESLVTAAYMPSIED----------------IVEL-- 785

  Fly  1028 KTHAGGKTSRQRLTTTTNR---IPVTTFRRGGAAAAEYFTSTTPGYTTTTDLPTTTGLGAGSYEE 1089
                    .::||..|..:   .|:......|.|.......:||........||.........||
  Fly   786 --------VKERLDQTPKKDQMAPMELILTPGGAEPMSLVQSTPEQLEPESQPTEEAASTAGQEE 842

  Fly  1090 TTKFEI--RVEDLEEATT--TTAPLLEVNSDRRAL 1120
            .....|  ||...|.|.:  .|.|:.....|..||
  Fly   843 EVILPIYKRVSTAEPAMSKVQTLPVTVSKVDTEAL 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
thw	NP_001097699.2	CBM_14	112..164	CDD:426342	25/64 (39%)
CG12009	NP_647799.1	CBM_14	82..145	CDD:426342	25/64 (39%)
		PRK10263	<203..>357	CDD:236669	38/245 (16%)