Protein Alignment CG14605 and HXT1

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 476
• Identity: 115/476 - (24%)
• Similarity: 206/476 - (43%)
• Gaps: 77/476 - (16%)

  Fly     6 GISLGWFSPTLPTLISDNSPI----------GHPIDISEVKWIGASFGIGCLICNMVICVPVSYF 60
            |...||.:.|:...::....:          .|.:.......|.:.|.|||.|..:|:......:
Yeast    76 GFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMY 140

  Fly    61 GIKKCMYFVPLPNILNWVLIYFAS--KSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTL 123
            |.:..:..|.:...:. ::|..||  |...:::.|::.|:..|.:.|..|:.|:||:.:.:||||
Yeast   141 GRRIGLIVVVVIYTIG-IIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTL 204

  Fly   124 GSFFMMTLCSGITVGFVLVYCLSYHV----------LPCVVIFLPILYLC-LIIPLPEPPQDLLK 177
            .|.:.:.    ||:|..|.||.::..          :|..:.|...|::. .::.:||.|:.|::
Yeast   205 VSCYQVM----ITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVE 265

  Fly   178 RGHEEKAEKSFCFYKNLSKDPAQQDDNKAEFDKLR---NKVLASGIA---EKIT--PADFFNKVS 234
            .|..::|..|..   .::|.|......:.|.:.:.   .::.|:|.|   |..|  ||.|...:.
Yeast   266 AGRIDEARASLA---KVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMM 327

  Fly   235 GKAFGLIAVLLLS-NQMSGSFAIFNYSSTIFEQLG--SRMEPNLCGIFLGVVQIFGLISAVLLVD 296
            |       :::.| .|::|....|.|.:.:|:.:|  ...|.:   |..|||..|....::..||
Yeast   328 G-------IMIQSLQQLTGDNYFFYYGTIVFQAVGLSDSFETS---IVFGVVNFFSTCCSLYTVD 382

  Fly   297 RVGRRLLLIPSLAGM---GLAELGVGLLKSFAS-QDFLHNNG----WIALTLMGIVSFTASAGIV 353
            |.|||..|:....||   .:....||:.:.:.: ||...:.|    .|......|..|..:...:
Yeast   383 RFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPI 447

  Fly   354 ALTFVIIVELLPFKIRAPGISIS-----MCGLSLSVFIALITYPVLINDYGVHVTM--FVSASFC 411
            |  :|:|.|..|.::::..:||:     :.|..:|.|...||  ..||.|..:|.|  .|.|.|.
Yeast   448 A--YVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFIT--GAINFYYGYVFMGCMVFAYFY 508

  Fly   412 LLGLVVLGIFLPETRGKSITQ 432
            :.      .|:|||:|.|:.:
Yeast   509 VF------FFVPETKGLSLEE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	115/474 (24%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	115/476 (24%)