Protein Alignment CG14605 and HXT4

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 114/481 - (23%)
• Similarity: 205/481 - (42%)
• Gaps: 87/481 - (18%)

  Fly     6 GISLGWFSPTLPTLISDNSPIGH--------PIDISEVK--WIGASFGIGCLICNMVICVPVSYF 60
            |...||.:.|:...::....|..        ...:|:|:  .|.:.|.|||.|..:::......:
Yeast    82 GFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMY 146

  Fly    61 GIKKCMYFVPLPNILNWVLIYFAS--KSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTL 123
            |.|..:..|.:..|:. ::|..||  |...:::.|::.|:..|.:.|..|:.|:|||...:||||
Yeast   147 GRKMGLIVVVVIYIIG-IIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTL 210

  Fly   124 GSFFMMTLCSGITVGFVLVYCLSYHV----------LPCVVIFLPILYLC-LIIPLPEPPQDLLK 177
            .|.:.:.    ||:|..|.||.:|..          :|..:.|...|::. .:..:||.|:.|::
Yeast   211 VSCYQLM----ITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVE 271

  Fly   178 RGHEEKAEKSFCFYKNLS-KDPAQQDDNKAEFDKLRNKVLASGIAEKITPADFFNKVSGKAFGLI 241
            .|..|:|::|......:| .|||..    ||.:.::..|.|..:|...:..:.|: ...|.|..:
Yeast   272 VGKIEEAKRSIALSNKVSADDPAVM----AEVEVVQATVEAEKLAGNASWGEIFS-TKTKVFQRL 331

  Fly   242 ---AVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNL-CGIFLGVVQIFGLISAVLLVDRVGRRL 302
               |::....|::|....|.|.:|:|..:|  :|.:. ..|.||:|........:.||:|.|||.
Yeast   332 IMGAMIQSLQQLTGDNYFFYYGTTVFTAVG--LEDSFETSIVLGIVNFASTFVGIFLVERYGRRR 394

  Fly   303 LLIPSLAGMG-----LAELGVGLL-----KSFASQDFLHNNGWIALTLMGIVSFTASAGIVALTF 357
            .|:...|.|.     .|.:||..|     |:.:|:.  ..|..|..|...:..|..:  ...:.|
Yeast   395 CLLWGAASMTACMVVFASVGVTRLWPNGKKNGSSKG--AGNCMIVFTCFYLFCFATT--WAPIPF 455

  Fly   358 VIIVELLPFKIRAPGISISMC-----GLSLSVFIALITYPVLINDYGVHVTMFVSAS------FC 411
            |:..|..|.::::..::|:..     |..:..|                 |.|:|.:      :.
Yeast   456 VVNSETFPLRVKSKCMAIAQACNWIWGFLIGFF-----------------TPFISGAIDFYYGYV 503

  Fly   412 LLGLVVLG-----IFLPETRGKSITQ 432
            .:|.:|..     .|:|||:|.::.:
Yeast   504 FMGCLVFSYFYVFFFVPETKGLTLEE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	114/479 (24%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	114/481 (24%)