Protein Alignment CG14605 and ITR2

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 471
• Identity: 103/471 - (21%)
• Similarity: 181/471 - (38%)
• Gaps: 74/471 - (15%)

  Fly     6 GISLGWFSPTLPTLISDNSPIGHPI-DISEVKWIGASFGIGCLICNMVICVPVSYFGIKKCMYFV 69
            |...|:.|   ..|||.|..:.:.: ...|.:.|.|:..:|.||.::........||.:.|:.|.
Yeast   124 GYDTGYIS---SALISINRDLDNKVLTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFS 185

  Fly    70 PLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSG 134
            .|..::..:|...|.|.......|:::|...|...:..|:||:|::...:||.|.....:.|..|
Yeast   186 NLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGG 250

  Fly   135 ITVGF--------------VLVYCLSYHVLPCVVIFLPILYLCLIIPLPEPPQDLLKRGHEEKA- 184
            ..:.:              :||   ...::|.|:.|   .:.|.   ||:.|:..:.:|..::|
Yeast   251 QLIAYGCGAGLNHVKNGWRILV---GLSLIPTVLQF---SFFCF---LPDTPRYYVMKGDLKRAK 306

  Fly   185 ---EKSFCFYKNLSKDPAQQDDNKAEFDKLRNKVLASGIAEKI---------TPADFFNKVSGKA 237
               ::|:     ::.:....|....|...|...:.......|.         .|::|...:.|
Yeast   307 MVLKRSY-----VNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIG-- 364

  Fly   238 FGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDRVGRRL 302
            .||.|:    .|.:|..::..:|.||||.:|.:....:..|..|...:|.|| |...:|::|||.
Yeast   365 CGLQAI----QQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLI-AFFCIDKIGRRY 424

  Fly   303 LLIPSLAGMGLAELGVGLLKSFASQDFLHNNGWIALTLMGIVSFTASAGIVALTFVIIV------ 361
            :|:..|.||.:|.:...:...|....|   ||..|:......|   |.|||.:.|:|:.
Yeast   425 ILLIGLPGMTVALVICAIAFHFLGIKF---NGADAVVASDGFS---SWGIVIIVFIIVYAAFYAL 483

  Fly   362 ----------ELLPFKIRAPGISISMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLV 416
                      ||.|..:|..|.|.:.........:...|:..::.:.....|....|....|..:
Yeast   484 GIGTVPWQQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTI 548

  Fly   417 VLGIFLPETRGKSITQ 432
            ......||..|..:.:
Yeast   549 FCYFCYPELSGLELEE 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	103/469 (22%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	100/461 (22%)