Protein Alignment CG14605 and MPH3

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_012694.1
• Gene: MPH3 / 853625
• SGDID: S000003921
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 484
• Identity: 98/484 - (20%)
• Similarity: 177/484 - (36%)
• Gaps: 133/484 - (27%)

  Fly    21 SDNSPIGHPIDISEVKW-IGASFGIGCLICNMV-ICVPVSYFGIKKCMYFVPLPNI--------L 75
            |.|...|        :| |.||:.||..:|.|. ..|.:...|          |::        |
Yeast   133 SQNDKTG--------EWEISASWQIGLTLCYMAGEIVGLQLTG----------PSVDLVGNRYTL 179

  Fly    76 NWVLIYFASKSLYFYVCRVLLGISGGTLVV-----CFPV----FIAEVSDNSVRGTLGSF----- 126
            ...|.:.|:.:...|.|..|..|:.|..:.     ||..    :.:|:...::|..|.::
Yeast   180 IIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCW 244

  Fly   127 -FMMTLCSGI-----------TVGFVLVYCLSYHVLPCVVIFLPILYLCLIIPLPEPPQDLLKRG 179
             |.....:||           .:|:.|.:.|.: :|| |.:.|.|.:      .||.|..|:|:|
Yeast   245 LFGQLFAAGIMKNSQKKYADSELGYKLPFALQW-ILP-VPLALGIFF------APESPWWLVKKG 301

  Fly   180 HEEKAEKSFCFYKNLS-KDPAQQDDNKAEFDKL-----RNKVLASGIAEKITPADFFNKVSGKAF 238
            ..::|.:|  ..:.|| |.|.::.....|.||:     :.|.|.|   ::.:.:|.|.....:..
Yeast   302 RFDEARRS--LRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTS---KEGSYSDCFEDKINRRR 361

  Fly   239 GLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPN-----------LCGIFLG----------V 282
            ..|..|..:.|.:....:..||:..:|:.|...|.:           :|..||.          .
Yeast   362 TRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYD 426

  Fly   283 VQIFGLISAVLLVDRVGRRLLLIPSLAGMGL-----AELGVGLLKSFASQDFLHNNGWIALTLMG 342
            :..|||....::...:|          |:|.     :::|.|                   :|:.
Yeast   427 LYAFGLAFQTIVFFIIG----------GLGCSSTHGSKMGSG-------------------SLLM 462

  Fly   343 IVSFTASAGIVALTFVIIVELLPFKIRAPGISISMCGLSLSVFIALITYPVLIN----DYGVHVT 403
            .|:|..:.||..:.|.::.|:...::|...|.::....::...|..:.....:|    ::|....
Yeast   463 AVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSG 527

  Fly   404 MFVSASFCLLGLVVLGIFLPETRGKSITQ 432
            .|... .|...|:...:.||||.||:..:
Yeast   528 FFWGV-LCFCTLIWAVVDLPETAGKTFVE 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	98/482 (20%)
MPH3	NP_012694.1	SP	72..556	CDD:273317	98/484 (20%)