Protein Alignment CG14605 and VPS73

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 463
• Identity: 111/463 - (23%)
• Similarity: 187/463 - (40%)
• Gaps: 109/463 - (23%)

  Fly    27 GHPIDISEVKWIGASFGIGCL--------ICNMVICVPVSYFGIKKCMYFVPLPNI--------- 74
            |:|.|.:   |:|......|:        |...|.|:.    ||....:...|.||
Yeast    67 GYPYDRT---WLGKRGYKQCIPLNDEQIGIVTSVFCIG----GILGSYFATSLANIYGRKFSSLI 124

  Fly    75 ---LNWV--LIYFASKSLY-FYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCS 133
               ||.|  ||.|.|.|.. ..:.|:|:|||.|:|:|..|:||.||:.:...|.|||  |..:|
Yeast   125 NCTLNIVGSLIIFNSNSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGS--MTQIC- 186

  Fly   134 GITVGFVLVYCLSYHVLPCV-------VIF----LPILYLCLIIPLPEPPQDLLKRGHEEKAEKS 187
             |.:|.:|...::   ||..       ::|    :.:|...:...:.|.|:.||..|....|:.|
Yeast   187 -IRLGVLLTQGIA---LPLTDSYRWRWILFGSFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLS 247

  Fly   188 FCFYKNLSKDPAQQDDNKAEFDKLRNKVLASG--IAEKITPADFFNKVSG--------------K 236
            .|..:.::.|.|.|:....:..      :.||  :.|..|.    |.:||              |
Yeast   248 LCKLRGVTFDEAAQEIQDWQLQ------IESGDPLIEPTTT----NSISGSNSLWKYLRDRTNVK 302

  Fly   237 AFGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDRVGRR 301
            :..:|.|||...|..|..:|..|.:.|..||..:....: ..|:.:|.:...|...||:..:.|:
Yeast   303 SRHVITVLLFGQQFCGINSIVLYGTKIISQLYPQHAIRI-NFFISMVNVLVTILVSLLIHSLPRK 366

  Fly   302 LLLIPSLAGMGLAELGVGLLKSFASQDFLHNNGWIALTLMGIVSF----TASAGIVALTFVIIVE 362
            .||:.|...:.:....:|:..:       ||.    :.|:.:.||    ..:.|:..|.|:|:.|
Yeast   367 PLLMTSTVLVSVTAFIMGIAMN-------HNK----MNLLIVFSFIYMGVFTMGLNPLPFIIMRE 420

  Fly   363 LLPFKIRAPGISI------SMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVLGIF 421
                 :..|...:      ::|.. :..||...|:|: |:|.   ::.:|...|.::...:....
Yeast   421 -----VSKPQDMVLAQRYGTICNW-VGTFIIAYTFPI-IHDV---LSGYVFIIFAIIACSISAFI 475

  Fly   422 ---LPETR 426
               :|||:
Yeast   476 WKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	111/463 (24%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	111/463 (24%)